It has been shown that certain symptoms in chicks, namely, exudative diathesis, yellow coloration of the adipose tissue, and encephalomalacia, and in rats, namely, yellowbrown coloration of the adipose tissue, and depigmentation of the incisors, depend upon the consumption of vitamin E-deficient diets rich in highly unsaturated fatty acids (Dam, 1944a, b ; Dam & Granados, 1945a, b ; Granados & ...