Runs of numerical computer programs can be visualized as directed acyclic graphs (DAGs). We consider the problem of restoring the intermediate values computed by such a program (the vertices in the DAG) in reverse order for a given upper bound on the available memory. The minimization of the associated computational cost in terms of the number of performed arithmetic operations is shown to be N...

To reveal the physiological and biochemical mechanism underlying graft union formation in pecan (Carya illinoinensis), dynamic changes content of nutrients, tannin, phytohormones together with key enzyme activities were investigated 0, 3, 5, 7, 10, 14, 18, 22, 31, 40 d after grafting (DAG), homograft unions. During formation, peroxidase (POD) activity increased at 7 - 10 DAG compared that 0 DAG...

ATP-competitive inhibitors of PKC (protein kinase C) such as the bisindolylmaleimide GF 109203X, which interact with the ATP-binding site in the PKC molecule, have also been shown to affect several redistribution events of PKC. However, the reason why these inhibitors affect the redistribution is still controversial. In the present study, using immunoblot analysis and GFP (green fluorescent pro...

We describe a new paradigm for implementing inference in belief networks, which consists of two steps: (1) compiling a belief network into an arithmetic expression called a Query DAG (Q-DAG); and (2) answering queries using a simple evaluation algorithm. Each node of a Q-DAG represents a numeric operation, a number, or a symbol for evidence. Each leaf node of a Q-DAG represents the answer to a ...

1,2-sn-Diacylglycerols (DAGs) are activators of protein kinase C (PKC), which is involved in the regulation of colonic mucosal proliferation. Extracellular DAG has been shown to stimulate the growth of cancer cell lines in vitro and may therefore play an important role in tumor promotion. DAG has been detected in human fecal extracts and is thought to be of microbial origin. Hitherto, no attemp...

We consider the NP{complete problem of generating evaluations for expression DAGs with a minimalnumber of registers. We restrict our attention to contiguous evaluations, because for nearly all of the DAGs derived from real application programs there exists a contiguous evaluation that is optimal w.r. to the register need. We present an algorithm that generates an optimal contiguous evaluation f...

The C1 domain mediates the diacylglycerol (DAG)-dependent translocation of conventional and novel protein kinase C (PKC) isoforms. In novel PKC isoforms (nPKCs), this domain binds membranes with sufficiently high affinity to recruit nPKCs to membranes in the absence of any other targeting mechanism. In conventional PKC (cPKC) isoforms, however, the affinity of the C1 domain for DAG is two order...

RasGRPs (guanine-nucleotide-releasing proteins) are exchange factors for membrane-bound GTPases. All RasGRP family members contain C1 domains which, in other proteins, bind DAG (diacylglycerol) and thus mediate the proximal signal-transduction events induced by this lipid second messenger. The presence of C1 domains suggests that all RasGRPs could be regulated by membrane translocation driven b...