The capsular polysaccharide of Type IX pneumococcus contains D-glucose, N-acetyl-D-glucosamine, and D-glucuronic acid. Complete hydrolysis is difficult. All of the N-acetylglucosamine is resistant to oxidation by periodate, but the other two sugars are degraded in part. Chemical and quantitative serological data are consistent with the linkage of two D-glucose residues 1 --> 4, as in maltose; o...

Abbreviations: BC: Bladder Cancer; MIBC: Muscle-Invasive BC; NMIBC: Nonmuscle-Invasive BC; BPH: Benign Prostatic Hyperplasia; CT: Computed Tomography; CEA: Carcinoembryonic Antigen; CA19-9: Carbohydrate-Antigen 19-9; HCC: Hepatocellular Carcinoma; TCC: Transitional Cell Carcinoma; UC: Urotherial Carcinoma; Hex: Hexose; Man: D-mannose; Gal: D-galactose; HexNAc: N-acetylhexsosamine; GlcNAc: N-ace...

Many patients with arthritis are using alternative modes of therapy, including nutritional supplements, to treat their arthritis. Most patients never tell their doctors that they are taking alternative medications, and few doctors even ask about such activities. Over-the-counter supplements are expensive and consume large amounts of patients' healthcare dollars. Glucosamine has been widely tout...

The lipopolysaccharides (LPSs) isolated from typhus group (TG) rickettsiae Rickettsia typhi and Rickettsia prowazekii were characterized by chemical analysis and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) followed by silver staining. LPSs from two species of TG rickettsiae contained glucose, 3-deoxy-D-manno-octulosonic acid, glucosamine, quinovosamine, phosphate, and f...

Background: Glucosamine and chondroitin sulfate are integral components of articular cartilage and they have important role to the physiologic and mechanical properties of this tissue. Glucosamine is acting as the precursor of the disaccharide unit in glucosaminoglycans (GAGs) of Cartilage Materials and method: The use of glucosamine and chondroitin sulfate for the symptomatic treatment of os...

In this study it could be shown that in rat the normally occurring N-acetyl neuraminic acid can be modified in its N-acyl moiety by in vivo administration of the chemically synthesized N-propanoyl precursors, N-propanoyl-D-glucosamine or N-propanoyl-D-mannosamine. It could be shown that each of these nonphysiological amino sugar analogues was incorporated into both membrane and serum glycoprote...

The first synthesis of the cyclopentitol units in bacterial hopanoids has been accomplished from D-glucosamine and the possible biological activity of the free cyclitols as glycosidase inhibitors has been studied.

A systematically varied series of conformationally restricted ketones, readily prepared from N-acetyl-D-glucosamine, were tested against representative olefins as asymmetric epoxidation catalysts showing useful selectivities against terminal olefins and, in particular, typically difficult 2,2-disubstituted terminal olefins.