Chrysanthemum zawadskii var. latilobum (CZ) has been used for beverage or tea and also as folk medicine for the remedy of diverse inflammatory diseases. Nevertheless, the therapeutic effect of CZ on arthritis remains to be unknown. In this paper we aim to investigate the CZ's antiarthritic effect and mechanism of action both in vitro and in vivo. To assess CZ's antiarthritic effect, mouse model...

Clinoptilolite type of zeolite (CZ) is a promising material for biomedicine and pharmaceutics due to its non-toxicity, thermal stability, expanded surface area, and exceptional ability to adsorb various atoms and organic molecules into micropores. Using multiphoton microscopy, we demonstrated that individual CZ particles produce two-photon excited luminescence and second harmonic generation sig...

1 Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, CZ-613 00 Brno, Czech Republic, European Union 2 Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, CZ616 00 Brno, Czech Republic, European Union 3 Department of Chemistry, and 4 Research Centre for Environmental Chemistry and Ecotoxicology, Faculty ...

In this paper we prove that the Diophantine equation x − 4cxy + (6c+ 2)xy + 4cxy + y = 1, where c ≥ 3 is an integer, has only the trivial solutions (±1, 0), (0,±1). Using the method of Tzanakis, we show that solving this quartic Thue equation reduces to solving the system of Pellian equations (2c+ 1)U − 2cV 2 = 1, (c− 2)U − cZ = −2, and we prove that all solutions of this system are given by (U...

Rarefied gas flows in ultra-thin film slider bearings are studied in a wide range of Knudsen numbers. The generalized Reynolds equation first derived by Fukui and Kaneko [1], [2] has been extended by allowing for bounding surfaces with different physical structures, as an issue of relevance for applications. Since the solution of this equation requires that the Poiseuille and Couette flow rates...

Let y(G) be the domination number of a graph G and let G U H denote the Cartesian product of graphs G and H. We prove that y(X) = (nr= ,nr)/(2m + l), where X = C1 0 CZ 0 ... 0 C, and all nt = ICkIr 1 < k < m, are multiples of 2m + 1. The methods we use to prove this result immediately lead to an algorithm for finding minimum dominating sets of the considered graphs. Furthermore the domination n...

Optical packet switching over arbitrary physical topologies typically mandates complex routing schemes and the use of buffers to resolve the likely contentions. However, the relatively immature nature of optical logic devices and the limitations with optical buffering provide significant incentive to reduce the routing complexity and avoid optical domain contentions. This paper examines how the...

Hydrogen sulfide (H2S) functions as a protective gas transmitter in various physiological and pathological processes, but the lack of ideal donors severely hampers the clinical application of H2S. This study aims to construct a controlled release H2S donor and evaluate its protective effect on graft endothelium. Mesoporous silica nanoparticles (MSNs) were synthesized using the sol-gel method an...

The prevailing view is that striatal parvalbumin (PV)-positive interneurons primarily function to downregulate medium spiny projection neuron (MSN) activity via monosynaptic inhibitory signaling. Here, by combining in vivo neural recordings and optogenetics, we unexpectedly find that both suppressing and over-activating PV cells attenuates spontaneous MSN activity. To account for this, we find ...

Mesh-based terrain representations provide accurate descriptions of a terrain, but fail in capturing its morphological structure. The morphology of a terrain is defined by its critical points and by the critical lines joining them, which form a so-called surface network. Because of the large size of current terrain data sets, a multi-resolution representation of the terrain morphology is crucia...