The aim of the study is to evaluate ethanol extract Rheum ribes root (RTE), as well and young shoots (RYSE), for its chemical composition, antioxidant properties cytotoxic effects. Total polyphenols (TPC), total flavonoid (TFC), radical scavenging activity (DPPH), ferric reducing power (FRAP) extracts were determined using colorimetric methods. Mineral contents vitamin values samples by ICP-MS ...

objective: the number of new cancer cases with considerable mortality is increasing worldwide. since the inability of current therapies in treatment of patients and prevention the progress of tumors with fewer side effects, implementation of new methods is needed. gene therapy has widespread systemic cytotoxic effects against tumor cells. rotavirus nsp4 has been shown to elicit extensive cytoto...

background and objectives: iran owns a rich and prestigious heritage of medicinal herbs but the majority of these plants have not yet undergone chemical, pharmacological and toxicological studies. in the present study some species form northern parts of iran were evaluated for cytotoxicity. methods: sixteen medicinal plants were extracted with methanol and screened for their cytotoxic activitie...

A new indole alkaloid named bufobutarginine (1), along with three known bufotenines, namely, serotonin (2), bufotenidine (3), and bufotenine (4), were isolated from the water extract of toad venom. Their structures were elucidated by spectral methods. This is the first time that arginine has been found to be involved in the biosynthesis of bufotenines in parotid of toad. The cytotoxic activitie...

A new compound, 1,2-di-(syringoyl)-β-D-glucopyranose, together with erigeside C, were isolated from the roots of Acanthus ilicifolius. The structure of the new compound was elucidated by extensive spectroscopic methods, including 1D, 2D NMR and HRESIMS spectroscopic data. The cytotoxic activities of these compounds were evaluated against HepG2, A-549, and HeLa cells in vitro. However, none of t...

Objective(s): Mindium laevigatum is an endemic plant of Iran and Turkey and is widely used as blood purifier, antiasthma and antidyspnea in traditional medicine. Chemical composition of volatile materials of the plant and its antioxidant, antimicrobial and cytotoxic activities were reported in this study. Materials and Methods: Simultaneous distillation-extraction (SDE) and GC-Mass-FID analysis...