background: calprotectin is cytotoxic agent that its anti-tumor effects are governed through suppression of topoisomerase ii a key enzyme in apoptosis. in previous studies, cytotoxicity and apoptotic effects of calprotectin are shown on different cancer cell lines, but not human gastric cancer cell lines. in the present study, cytotoxicity and apoptotic effects of calprotectin on human gastric ...

cervical cancer is the most common gynecologic cancer and the second most common cancer in women worldwide. herbal preparations are used to treat cancer for centuries. the aim of this study was investigate the cytotoxic effects of the methanol extract of citrullus colocynthis and volatile oils of iranian c. medica on hela cell line. after preparation extract and volatile oils, different concent...

Our present and previous findings may be summarized as follows: The phenotype of C57BL/6 (B6) cytotoxic cells for allogeneic target cells is Thy-1+, Ly-1- Ly-2/3+, MSLA+, and Ig-. the phenotype of B6 cytotoxic cells for syngeneic tumor cells is Thy-1+, Ly-1+, Ly-2/3+, MSLA+, and Ig-. The phenotype of B6 cytotoxic cells for syngeneic tumor cells is Thy-1+, Ly-1+, Ly-2/3+, MSLA+, AND Ig-. Thus, d...

Synthesis of Silver Nanoparticles using Methanol Extract Bunium Persicum and the Evaluation its Cytotoxic, Antileishmanial, Antimicrobial Activities

42 human sera showing in vitro cytotoxic activity of restricted or broad HL-A specificities with test human lymphocytes were studied for the molecular and immunoglobulin class of cytotoxic antibody using sucrose gradient separations, DEAE-cellulose chromatography, and Sephadex G-200 gel filtration. Sera originated from patients with previous multiple pregnancies (19), multiply transfused patien...

In vitro Cytotoxic Effect of Biosurfactant Extracted from Bifidobacterium spp. on MCF-7 and WRL68 Cell Lines

Comparison the cytotoxic effects of Ulva fasciata and lactuca on MCF-7 MDA-MB-231breast cancer cell lines

Cytotoxic T lymphocytes (CTLs) eliminate infected and neoplastic cells through directed release of cytotoxic granule contents. Although multiple SNARE proteins have been implicated in cytotoxic granule exocytosis, the role of vesicular SNARE proteins, i.e., vesicle-associated membrane proteins (VAMPs), remains enigmatic. VAMP8 was posited to represent the cytotoxic granule vesicular SNARE prote...

The venoms of the Naja species are known to be cytotoxic. This toxicity has been attributed to the presence of small nonenzymatic polypeptides of 60 amino acid residues, designated as cardiotoxins or cytotoxins. We investigated the cytotoxic potency of Naja nigricollis venom fractions and isolated another type of cytotoxic component which is even more potent than cardiotoxins. This cytotoxic co...

A series of 2-amino-4-(nitroalkyl)-4H-chromene-3-carbonitriles were synthesized by an efficient multicomponent reaction in aqueous media using DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) as a catalyst at room temperature. Mild condition, environment friendly procedure and excellent yields are the main advantages of this procedure. The cytotoxic activity of target compounds were evaluated against t...