Malignant mesotheliomas are aggressive cancers that occur in the thin layer of tissue covers most commonly linings chest or abdomen. Though cancer itself is rare and deadly, early diagnosis will help with treatment improve outcomes. Mesothelioma usually diagnosed later stages. Symptoms similar to other, more common conditions. As such, predicting diagnosing mesothelioma essential starting for a...

cystic hygroma is a well-recognized lesion in paediatric patients but it is very rare in adults. we report here a case of cervical cystic hygroma in a 45 yr old male. the reasons to present this case are 1) its rarity in adults 2) unusual age of presentation 3) simulates various benign and malignant lesions at this site 4) is a diagnostic challenge and 5) role of histology for definitive postop...

how to cite this article: ashrafi mr, tavasoli ar. cystic leukoencephalopathy. iran j child neurol. autumn 2014; 8:4(suppl. 1):3-4. pls see pdf.

For the present study, and follow-up of histochemical changes in estradiol valerate-induced polycysticovary syndrome (PCOS), 48 virgin 90-day-old female rats were used. The rats were divided into thetreatment and control groups. For each rat of the treatment group, 4 mg estradiol valerate was injectedthrough intramuscular route for the induction of PCOS. The control group was taken the same amo...

Although SV40 oncoproteins have been detected in malignant pleural mesotheliomas (MPMs), their role in the pathogenesis and clinical behavior of these neoplasms remains controversial. In the present study, we sought to define the relevance of SV40 T/t antigen expression in established human mesothelioma cell lines deficient for p16INK4a as well as ARF expression. SV40 early region sequences wer...

Injection of strain MC29 avian leukosis virus into the peritoneal, pericardia!, and air sac cavities of the chicken resulted in high incidence of tumors of the mesothelium of the respective structures. As determined by light and electron microscopy, the growths arose as papillomas or expanding tumors by alteration of the squamous mesothe lium to spheroidal or cuboidal cells characterized by rou...

BACKGROUND Malignant pleural mesothelioma (MPM) is a highly aggressive tumour first-line treated with a combination of cisplatin and pemetrexed. MDM2 and P14/ARF (CDKN2A) are upstream regulators of TP53 and may contribute to its inactivation. In the present study, we now aimed to define the impact of miRNA expression on this mechanism. MATERIAL AND METHODS 24 formalin-fixed paraffin-embedded ...