Development of more effective and less toxic antifungal agents is required for the treatment of dermatophytosis. Plants and their extraction preparations have been used as medicines against infectious diseases. In this research, the lemon grass [Cymbopogon citrates DC.) Stapf.], lantana (Lantana camara L.), nerium (Nerium oleander L.), basil (Ocimum basilicum L.) and olive leaves (Olea europaea...

BACKGROUND Dengue fever regardless of its serotypes has been the most prevalent arthropod-borne viral diseases among the world population. The development of a dengue vaccine is complicated by the antibody-dependent enhancement effect. Thus, the development of a plant-based antiviral preparation promises a more potential alternative in combating dengue disease. METHODS Present studies investi...

AIMS The current study was designed to document medicinal plant species that are traditionally used to treat tuberculosis (TB) by Ghanaian communities. METHODS The medicinal plants used against TB or its signs and symptoms were selected using library and online published data searches. A guided questionnaire interview was also conducted with a botanist involved in plant collection at the Cent...

BACKGROUND Essential oils (EOs) are complex mixtures of secondary metabolites from various plants. It has been shown that several EOs, or their constituents, have inhibitory activity against trypanosomatid protozoa. Thus, we analyzed the biological activity of different EOs on Trypanosoma cruzi, as well as their cytotoxicity on Vero cells. METHODS The following EOs were evaluated on T. cruzi ...

Generally, the medicinal plants have antifungal substances that can be used for the plant protection against phytopathogens. The objective of this study was to know the efficiency of aqueous extracts from medicinal plants against the major etiological agents of coffee tree. The aqueous extracts used were extracted from bulbs of Allium sativum, leaves of Vernonia polysphaera, Cymbopogon citratus...

ETHNOPHARMACOLOGICAL RELEVANCE Aqueous extracts of Cymbopogon citratus (Cy) leaves are used in traditional medicine for the treatment of inflammatory conditions, however, little is known about their mechanism of action. AIM OF THE STUDY The aim of this study is to explore the anti-inflammatory properties of Cymbopogon citratus leaves and their polyphenol-rich fractions (PFs), as well its mech...

Objective: To evaluate lipoxygenase inhibitory, antioxidant, and antimicrobial activities of selected essential oils. Materials and Methods: Essential oils were obtained by hydro distillation using a Clevenger-type apparatus and oils composition was analyzed by gas chromatography-mass spectrometry. Lipoxygenase inhibitory activity of essential oils was evaluated by lipoxygenase inhibition assay...

BACKGROUND Khaya grandifoliola (C.D.C.) stem bark, Cymbopogon citratus (Stapf) and Cryptolepis sanguinolenta (Lindl.) Schltr leaves are used in Cameroonian traditional medicine for the treatment of inflammatory diseases. Several studies have been performed on the biological activities of secondary metabolites extracted from these plants. However, to the best of our knowledge, the anti-neuro inf...

Helminth infections are still a threat to public health for people resident in the tropics and underdeveloped countries. These infections are usually ignored and some of them, such as neurocysticercosis are dangerous and have serious side effects. The use of drugs on one hand assists to cure the diseases, but on the other hand, may cause the parasite to be resistant to treatment. These drugs ma...

The 1-deoxy-d-xylulose-5-phosphate reductoisomerase (DXR; EC1.1.1.267), an NADPH-dependent reductase, plays a pivotal role in the methylerythritol 4-phosphate pathway (MEP), in the conversion of 1-deoxy-d-xylulose-5-phosphate (DXP) into MEP. The sheath and leaf of citronella (Cymbopogon winterianus) accumulates large amount of terpenes and sesquiterpenes with proven medicinal value and economic...