نتایج جستجو برای: cyclic heptapeptide
تعداد نتایج: 98860 فیلتر نتایج به سال:
The heptapeptide angiotensin (Ang)-(1-7) is currently considered one of the biologically active end products of the renin-angiotensin system. The formation of Ang-(1-7) by pathways independent of Ang II generation, the selectivity of its actions, and its peculiar property of exhibiting effects that are partially opposite of those of the parent compound, Ang II, confer a unique biochemical and f...
We describe the design and synthesis of a peptidomimetic library derived from the heptapeptide Ac-RDVLPGT-NH 2, belonging to the Toll/IL-1 receptor (TIR) domain of the adaptor protein MyD88 and effective in inhibiting its homodimerization. The ability of the peptidomimetics to inhibit protein-protein interaction was assessed by yeast 2-hybrid assay and further validated in a mammalian cell syst...
the article introduces cyclic dilation groups and finite affine groups for prime integers, and as an application of this theory it presents a unified group theoretical approach for the cyclic wavelet transform (cwt) of prime dimensional periodic signals.
The increasing incidence of mass developments of Cyanobacteria in freshand brackish water is a matter of growing concern due to the production of toxins that threaten human and livestock health. The toxins that are produced by freshwater Cyanobacteria comprise hepatotoxins (cyclic peptides such as microcystins and nodularin, as well as alkaloids such as cylindrospermopsin) and neurotoxins (alka...
The ability of a,a-di-n-alkyl glycines with linear and cyclic alkyl side chains to stabilize helical conformations has been compared using a model heptapeptide sequence. The conformations of five synthetic heptapeptides (Boc–Val–Ala–Leu–Xxx–Val–Ala–Leu–OMe, Xxx 5 Ac8c, Ac7c, Aib, Dpg ,and Deg, where Ac8c 5 1-aminocyclooctane-1-carboxylic acid, Ac7c 5 1-aminocycloheptane1-carboxylic acid, Aib 5 ...
we present a 24-year-old female referred with non-healing wound of a few days duration on anterior aspect of her right foreleg. biopsy of the wound was reported to be pyoderma gangrenosum on pathologic report. further work up of the patient for high grade fever and occasional leukopenias revealed the diagnosis of cyclic neutropenia. treatment with granulocyte colony-stimulating factor (g-csf) r...
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