Since Ernst Fuchs's publication on sarcoma of the uveal tract,' in which he stated that malignant melanoma does not metastasise to the eye, more than 40 cases have been reported.2-28 An autopsy series of 15 patients who had died from disseminated cutaneous malignant melanoma, and who had no ocular symptoms, showed a 33% incidence of ocular metastases.29 The case is reported here of a man who, b...

This case report describes an exacerbation of AIDS-associated Kaposi sarcoma (KS) in the setting of iatrogenic Cushing syndrome caused by an interaction between ritonavir-boosted atazanavir and fluticasone. Discontinuation of fluticasone resulted in resolution of the cutaneous KS. Clinicians should be aware of this potential drug-drug interaction that can result in increased corticosteroid leve...

Results: Six patients (0.4%) developed Kaposi's sarcoma. Pathological diagnosis was established early after transplantation (mean interval of 23 months). The ratio of male to female patients was 5 to 1 (with no correction for the differential transplant rates between genders) and the mean age at the time of diagnosis was 44 years. All patients had cutaneous or mucosal lesions and visceral invol...

ABSTRACT Epidermoid cyst is a common benign cutaneous swelling frequently encountered in surgical practice. It usually presents as a painless lump frequently occurring in hairbearing areas of the body particularly the scalp, scrotum, neck, shoulder and back. Giant epidermoid cysts commonly occur in hairy areas such as the scalp. We present here the case of a rare occurrence of a giant epidermoi...

Primary nasolacrimal duct malignacy is rare. Only a few tumours have been reported originating from this location including lymphoma, Kaposi’s sarcoma, adenocarcinoma, angiofibroma, and squamous cell carcinoma. Mucosal melanoma represents 1–2% of all melanomas, with 25–50% in the head and neck—that is, upper respiratory tract, oral cavity, and pharynx. Other sites include urinary, female genita...

Kaposi's sarcoma (KS) typically presents multiple cutaneous lesions of the lower extremities. Lesions can rarely mimic varicose veins without venous insufficiency, vascular or stasis ulcers. As the initial diagnosis of KS is generally determined clinically, a high index of suspicion and palpation of lesions are necessary for all patients with atypical presentations of varicose-like lesions of l...

Between 1994 and 2011, an average of 6,899 cases of invasive skin cancer was diagnosed per year in Ireland. Malignant melanoma accounted for just over 8% of this number; the vast bulk of all invasive skin cancers being non-melanomatous subtypes, of which over 6,300 were diagnosed each year (Table 1). Over 95% of these “nonmelanoma” skin cancers were histologically diagnosed and almost all were ...

Purpose. The prognosis of advanced soft tissue sarcoma is poor, only a few drugs showing some activity with response rates around 15- 25%. Consequently drug development seems mandatory to improve treatment outcome. Following previous favourable EORTC experience, the Italian Group on Rare Tumors started a phase II study with docetaxel to confirm the activity of this drug in soft tissue sarcoma.P...

BACKGROUND Kaposi sarcoma (KS) has features of both neoplastic growth and hyperplastic proliferation. It is the most common tumor seen in patients with HIV infection. Whether KS is a real tumor or a benign hyperplastic disease is not known. MATERIAL AND METHODS Tissues from KS and cutaneous hemangioma lesion DNA were extracted, and then digested with methylation-sensitive restriction endonucl...