chronic granulomatous disease (cgd) is a rare disorder of phagocytes, predisposes patients to bacterial and fungal infections. the main purpose of this study was to determine the clinical, radiological, pathologicial features, outcome and response to treatment of children with cgd. thirteen patients with cgd, who had been referred to national research institute of tuberculosis and lung disease ...

BACKGROUND Increasing evidences support the role of Merkel cell polyomavirus (MCPyV) and human papillomavirus (HPV) in non-cutaneous and cutaneous tumours. Porocarcinoma is a rare malignant neoplasm that arises from the intraepidermal ductal portion of the eccrine sweat glands. The aetiology of porocarcinoma is largely unknown and no systematic studies have been done to investigate the implicat...

Aspergillosis and candidosis remain the most prevalent opportunistic fungal infections in immunocompromised patients, but diseases caused by the Zygomycetes have become of increasing importance. Exposure to antimycotic drugs with no activity against zygomycetes may be a new risk factor and an explanation for the increasing incidence of zygomycosis. The latter infection occurs only rarely in imm...

Human infections due to Phialophora richardsiae, first described in 1968, is usually associated with subcutaneous cysts, although there have been reported cases of ulcerative lesions with discharging sinuses as well as infection of bones and tendon sheaths.1,2,3 Because infections bv P.richardsiae are rare and the fungus relatively unknown in Malaysia, it was thought worthwhile to report the is...

This specimen was designated as a sample “from a skin wound” that was to be cultured, identified to species level and susceptibility tested [1-3]. The culture contained a Streptococcus agalactiae (serogroup B) often associated with cutaneous infections and serious invasive perinatal/neonatal infections [4]. This strain has several antimicrobial resistances (discussed below) and was distributed ...

clericuzio-type poikiloderma with neutropenia (pn) is characterized by poikiloderma, non-cyclic  neutropenia,  recurrent  sinopulmonary  infections,  pachyonychia,  and  palmo- plantar hyperkeratosis. mutations in the c16orf57 gene, which is located on chromosome 16q13, have been identified as the cause of pn. pn was first described by clericuzio in navajo indians. herein, we reported the clini...