conclusions post immunization lv is a rare complication of the bcg vaccine and should be considered by any physician. lupus vulgaris is a paucibacillary form of tb. therefore, acid fast bacilli are not detected in most cases. the pcr is a useful method for confirmation of the diagnosis of lv. introduction lupus vulgaris (lv) is one type of cutaneous tuberculosis (tb) but a rare complication of ...

Toxic Epidermal Necrolysis (TEN) is a rare and often fatal muco-cutaneous disease usually related to severe adverse drug reaction. The standard treatment of TEN remains controversial and to our knowledge, all reports in literature are mostly concentrated on systemic therapy. On the contrary, no report deals with deep skin scars that may occur. We therefore present an original case of a severe s...

Mycobacterium massiliense which is recognized as a separate species from M. abscessus is little known regarding its clinical patterns and the response to treatment. We present a case of a localized cutaneous infection due to M. massiliense of the sole associated with acupuncture. M. massiliense was identified via polymerase chain reaction-hybridization analysis. We treated the patient with sing...

Acute generalized exanthematous pustulosis (AGEP) is a rare severe cutaneous adverse reaction caused mostly by medication. Early diagnosis is important as initiation of supportive treatment and avoidance of drug is of prime importance. A young male presented with an erythematous rash after taking diclofenac for pain. Polarized dermoscopy revealed milky globules on a uniform reddish background s...

Etofenamate is a non-steroidal anti-inflammatory drug (NSAID). Clinical findings caused by etofenamate are uncommon. Allergic contact dermatitis is the most common cutaneous reaction reported. But petechial eruption due to etofenamate had not been reported yet. This report concerns an 11-year old male with petechial eruption after application of topical etofenamate. Physicians need to be aware ...

Adverse cutaneous manifestations are among the most common side effects associated with psychotropic drugs. Skin reactions due to amitriptyline (a tricyclic antidepressant agent) include rashes and hypersensitivity reactions (for example, urticaria and photosensitivity) as well as hyperpigmentation. Hypersensitivity syndrome is a specific severe idiosyncratic reaction causing skin, liver, joint...

Case 1: A 43 year-old, white man presented with a four month-history of six plaques well-circumscribed. Laboratory results, including several serological tests, as well as a radiological investigation, were either negative or normal. The Mitsuda reaction was positive (9 mm). He was put on prednisone therapy and multi-drug therapy (MDT) with subsequent healing of the cutaneous lesions and improv...

Nicolau Syndrome (also known as Embolia cutis medicamentosa and livedo-like dermatitis) is a rare but severe localized adverse drug reaction to a range of intra-muscular preparations. It manifests as acute pain, cutaneous, subcutaneous and intra-muscular inflammation and necrosis immediately following an injection, with potentially devastating sequelae. We describe the syndrome in a 21-year-old...

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a type of severe adverse cutaneous drug reaction characterized by fever, skin eruption, hematological abnormalities, and internal organ involvement. Although anticonvulsant drugs are mainly implicated in DRESS, newer anticonvulsants such as oxcarbazepine-induced definite cases of DRESS syndrome are rare and oxcarbazepine-indu...

Sorafenib is a new oral drug currently approved for the treatment of metastatic renal cell carcinoma and hepatocellular carcinoma. The drug acts partly by inhibiting the tyrosine kinase receptors implicated in angiogenesis and tumor progression, and partly by blocking Raf kinase pathways. Up to 90% of patients receiving this treatment are reported to develop dermatological sideeffects. Hyperker...