نتایج جستجو برای: cure cycle optimization

تعداد نتایج: 613587  

2013
Ilona Hauber Helga Hofmann-Sieber Jan Chemnitz Danilo Dubrau Janet Chusainow Rolf Stucka Philip Hartjen Axel Schambach Patrick Ziegler Karl Hackmann Evelin Schröck Udo Schumacher Christoph Lindner Adam Grundhoff Christopher Baum Markus G. Manz Frank Buchholz Joachim Hauber

Stable integration of HIV proviral DNA into host cell chromosomes, a hallmark and essential feature of the retroviral life cycle, establishes the infection permanently. Current antiretroviral combination drug therapy cannot cure HIV infection. However, expressing an engineered HIV-1 long terminal repeat (LTR) site-specific recombinase (Tre), shown to excise integrated proviral DNA in vitro, may...

2015
Youlin Deng Junhui Zhang Zhongliang Wang Zhengjian Yan Min Qiao Jixing Ye Qiang Wei Jing Wang Xin Wang Lianggong Zhao Shun Lu Shengli Tang Maryam K. Mohammed Hao Liu Jiaming Fan Fugui Zhang Yulong Zou Junyi Liao Hongbo Qi Rex C. Haydon Hue H. Luu Tong-Chuan He Liangdan Tang

Ovarian cancer is the most lethal gynecologic malignancy with an overall cure rate of merely 30%. Most patients experience recurrence within 12-24 months of cure and die of progressively chemotherapy-resistant disease. Thus, more effective anti-ovarian cancer therapies are needed. Here, we investigate the possibility of repurposing antibiotic monensin as an anti-ovarian cancer agent. We demonst...

Journal: :journal of research in health sciences 0
mina hoseini abbas bahrampour moghaddameh mirzaee

background: breast cancer is the most common cancer after lung cancer and the second cause of death. in this study we compared weibull and lognormal cure models with cox regression on the survival of breast cancer. study design: a cohort study. methods: the current study retrospective cohort study was conducted on 140 patients referred to ali ibn abitaleb hospital, rafsanjan southeastern iran f...

F. A. Senel H. Ozturk S. Aytar

This study has developed a production inventory model where the cycle timeis fuzzy, the existence of defective products is assumed in each batch andproduct screening is performed both in-production and after-production.Triangular fuzzy numbers serve to model uncertainties in the cycle time, anda fuzzified total inventory profit function is created by thedefuzzifica...

2005
Khalid Alhumaizi AbdelHamid Ajbar

A procedure for the optimization of an unstructured first-order kinetics model of cyclically operated biological reactors for the biodegradation of a single pollutant is developed using a combination of analytical and numerical tools. Asymptotic analytical profiles for the substrate and biomass for each steady cycle are obtained that allows the formulation of an analytical design equation that ...

Journal: :journal of dentistry, tehran university of medical sciences 0
mr rouhollahi assistant professor, department of operative dentistry, faculty of dentistry, shahed university, tehran, iran. m mohammadibasir sh talim

depth of cure of composite material is restricted and it depends on many parameters such as thickness. the aim of this in-vitro study was to evaluate the depth of cure of two light-cured core build-up composites (quixfil and photocore) in different thicknesses, when cured for 60 seconds.the vickers microhardness measurements were made for each side of the top irradiated surfaces of 1,2,3,4,5,6,...

Journal: :journal of dental biomaterials 0
farnaz farahat department of operative dentistry, school of dentistry, shahid sadoughi university of medical sciences, yazd, iran alireza daneshkazemi social determinants on oral health research center and department of operative dentistry, school of dentistry, shahid sadoughi university of medical sciences, yazd, iran zeynab hajiahmadi yazd dental school, shahid sadoughi university of medical sciences, yazd, iran

statement of problem: for many years, application of the composite restoration with a thickness less than 2 mm for achieving the minimum polymerization contraction and stress has been accepted as a principle. but through the recent development in dental material a group of resin based composites (rbcs) called bulk fill is introduced whose producers claim the possibility of achieving a good rest...

2014
WANG Weida HAN Lijin XIANG Changle MA Yue

Now the optimization strategies for power distribution are researched widely, and most of them are aiming to the optimal fuel economy and the driving cycle must be preknown. Thus if the actual driving condition deviates from the scheduled driving cycle, the effect of optimal results will be declined greatly. Therefore, the instantaneous optimization strategy carried out on-line is studied in th...

دکتر علی نجفی, , دکتر لطف گچکار, , زینب خالدیان, , لیلا تک فلاح, , ناهید فتحی زاده, ,

Introduction & Objective: Premenstrual syndrome (PMS) is a common  cause of substantial psychological and physical distress for women during their reproductive years that occurs luteal phase  and  reduced their quality of life . Despite the magnitude of this problem, there was no effective treatment for PMS. Evening primrose oil was used traditionally for PMS but the cure effects are still ambi...

Abolghasem Ajami, Alireza Rafiei, Eshrat Gharaee, Fatemeh Rahbarizadeh, Mohammad bagher Hashemi Sooteh, Mohammad Soltany-Rezaee-Rad, Negar Mottaghi-Dastjerdi, Saeid Abediankenari,

Background: RNAi (RNA interference) is a new strategy in gene therapy and biotechnology which provides new promises in the treatment of different diseases such as cancer and viral diseases. CCND1 which is a key gene in cell cycle is amplified and over expressed in esophageal cancer. The objective of this study was production and siRNAs for CCND1, the key gene in cell cycle. Materials and Metho...

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