نتایج جستجو برای: cumulative dose

تعداد نتایج: 375131  

2017
Chin-Hsiao Tseng

This study investigated whether rosiglitazone may affect breast cancer risk in female patients with type 2 diabetes mellitus in Taiwan. The reimbursement database of all female patients with type 2 diabetes mellitus under oral antidiabetic agents or insulin from 1996 to 2009 was retrieved from the National Health Insurance. An entry date was set on 1 January 2006 and a total of 431447 patients ...

Journal: :Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2016
Robert D Frisina Heather E Wheeler Sophie D Fossa Sarah L Kerns Chunkit Fung Howard D Sesso Patrick O Monahan Darren R Feldman Robert Hamilton David J Vaughn Clair J Beard Amy Budnick Eileen M Johnson Shirin Ardeshir-Rouhani-Fard Lawrence H Einhorn Steven E Lipshultz M Eileen Dolan Lois B Travis

PURPOSE Cisplatin is widely used but highly ototoxic. Effects of cumulative cisplatin dose on hearing loss have not been comprehensively evaluated in survivors of adult-onset cancer. PATIENTS AND METHODS Comprehensive audiological measures were conducted on 488 North American male germ cell tumor (GCT) survivors in relation to cumulative cisplatin dose, including audiograms (0.25 to 12 kHz), ...

2012
Jaroslaw T. Hepel Justin Peter Jessica R. Hiatt Salil Patel Oluwademilade Osibanjo Howard Safran Bruce Curran Thomas DiPetrillo

PURPOSE Standard chemoradiation therapy for stage III non-small cell lung cancer (NSCLCa) results in suboptimal outcomes with a high rate of local failure and poor overall survival. We hypothesize that dose escalation using stereotactic body radiotherapy (SBRT) boost could improve upon these results. We present here a study evaluating the dosimetric feasibility of such an approach. METHODS An...

A. Derakhshan G. Hosseini-Al-Hashemi M. Basiratnia M.H. Fallahzadeh,

AbstractBackground: Given the high relapse rate of disease in children with steroid dependent nephrotic syndrome and the osteoporotic effect of long periods of steroid therapy, this survey was performed to find the bone mineral status of these patients. Methods: Bone mineral density and content (BMD and BMC) were measured using Dual energy X-ray absorptiometry in 37 nephrotic children, six girl...

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