DPNH cytochrome c reductase activity has been found associated with the MP virus isolated from the infected allantoic fluids or yolk sacs of fertile eggs and treated with trypsin, perfringens toxin, and cobra venom. The corresponding normal tissue enzymes can be nearly completely destroyed by such treatment, also the small activity found in crude preparations of influenza virus is destroyed by ...

Crotalus durissus cumanensis, a rattlesnake endemic to Colombia and Venezuela, is considered one of the most lethal snake species in Latin America. The aim of the present study was to compare the protein content and biological activity of the venom obtained from eight specimens of C. durissus cumanensis, namely two adults from different localities of Colombia and six offspring born in captivity...

EFFECT OF El7MTI FUNC.T]DN'AL GROUP INBI3ITORS ON PRGIE)0LTELYT ZYBMKU OF TA-3 S ATMO' WIEi1N C C43T To determine the effects of several functionaL group,-specific inhib=Qrsof enzymes and: of metal ioneon. the activityof the proteolytic enzymes of Crotalusatrmx venom.. To attempt M discern the typeand: number of proteolytic enzymes presenti m crude venom and: to obtain & detoxified,, yet immu.n...

Many snake venoms comprise different factors, which can either promote or inhibit the blood coagulation pathway. Coagulation disorders and hemorrhage belong to the most prominent features of bites of the many vipers. A number of these factors interact with components of the human blood coagulation. This study is focused on the effect of Echis carinatus snake venom on blood coagulation pathway. ...


 The reported cases of snake bite are 5.4 million per year, making the serious envenoming issue so, that WHO categorises in neglected tropical diseases. Anti venom is produced by intramuscular injection crude with different formulation adjuvants to equine animals, but these injections have several health impact equine. Snake species categorised according geographical locations, and there ...

Envenomation by Loxosceles bites is characterized by dermonecrotic and/or systemic features that lead to several clinical signs and symptoms called loxoscelism. Dermonecrotic lesions are preceded by thrombosis of the dermal plexus. Recent studies show that atheromatous plaque is prone to thrombosis due to endothelial cell apoptosis. To the best of our knowledge, there are no reports of microsco...

Phospholipase A₂s (PLA₂) is a major component of snake venom with diverse pathologic toxicities and, therefore, a potential target for antivenom therapy. Varespladib was initially designed as an inhibitor of mammal PLA₂s, and was recently repurposed to a broad-spectrum inhibitor of PLA₂ in snake venom. To evaluate the protective abilities of varespladib to hemorrhage, myonecrosis, and systemic ...

Sol i 2 is a potent allergen in Solenopsis invicta venom, and most humans exhibit reactivity to it. The Sol gem 2 allergen found in the venom of the Thai tropical fire ant Solenopsis geminata was analysed in the present study. The protein was present in higher amounts than other proteins, as determined by SDSPAGE, and presumably has allergenic properties similar to those of Sol i 2. Sol gem 2 m...

The venom of South African scorpion Parabuthus transvaalicus contains a novel group of peptide toxins. These peptides resemble the long chain neurotoxins (LCN) of 60-70 residues with four disulfide bridges; however they are 58 residues long and have only three disulfide bridges constituting a new family of peptide toxins. Here we report the isolation and characterization of three new members of...

Purpose: To determine the analgesic activity of Bungarus fasciatus venoms and their fractions from two Vietnamese Provinces.
 Methods: Male Swiss Albino mice were randomly divided into three groups containing 8 to 10 each. Control group was injected subcutaneously with normal saline, standard received aspirin solution (50 mg/kg) perorally, study a crude venom or isolated in physiological s...