This work highlights the rational design of recognitive networks via polymerization reaction analysis and detailed kinetic analysis for application in novel diagnostic or robust point-of-care devices. Non-covalent complexation interactions between template or ‘guest' biomolecules and functional monomers during polymerization can create networks with selective binding sites for biomolecules with...

Interest in tissue adhesives as alternatives for conventional wound closing applications, such as sutures and staples, has increased in the last few decades due to numerous possible advantages, including less discomfort and lower cost. Novel tissue adhesives based on gelatin, with alginate as a polymeric additive and crosslinked by carbodiimide were developed and loaded with two types of drugs ...

Composite materials can be prepared by the combination of at least two different phases, a continuous and a dispersed one. If one of these phases is on the nanometer scale, than the material is called a nanocomposite. In this context organic-inorganic hybrids stand for a new class of materials formed by two distinct compounds, the polymeric and ceramic, resulting in a crosslinked amorphous nano...

The synthesis and the characterization of new polymeric systems to be used as protective coatings for space vehicles is described. Particular emphasis is placed on ablators which have low irradiation and particle emissivity under the conditions of typical reentry of a space vehicle into the atmosphere. Crosslinking by ionizing radiation in carbon black filled Kel-F and Teflon has been establish...

Polymerization-induced self-assembly (PISA) is a versatile technique to achieve a wide range of polymeric nanoparticle morphologies. Most previous examples of self-assembled soft nanoparticle synthesis by PISA rely on a growing solvophobic polymer block that leads to changes in nanoparticle architecture during polymerization in a selective solvent. However, synthesis of block copolymers with a ...

Multimodal imaging probes can provide diagnostic information combining different imaging modalities. Nanoparticles (NPs) can contain two or more imaging tracers that allow several diagnostic techniques to be used simultaneously. In this work, a complex coacervation process to produce core-shell completely biocompatible polymeric nanoparticles (HyCoS) for multimodal imaging applications is descr...

Hydroxypropyl methylcellulose (HPMC) was employed in this study to design controllable drug release systems because of its non-toxic nature, swelling properties. New interpenetrating polymer networks (IPN) of HPMC / tri-isocyanate crosslinked polyurethane (TCPU) could be prepared on the surfaces of IPN materials. To design "Novel Drug-carrying Matrix Systems", incorporation of novel structure i...

A series of novel Si-O-Si crosslinked organic/inorganic hybrid semi-crystalline polymers with shape memory properties was prepared from alkoxysilane-terminated poly(butylene succinate) (PBS) by water-induced silane crosslinking under organic solvent-free and catalyst-free conditions. The hydrolyzation and condensation of alkoxysilane end groups allowed for the generation of silica-like crosslin...

Ricinoloxazoline maleinate (OXA) was grafted by melt free radical grafting onto polyolefins and elastomers to produce new compatibilizers for polymer blends. Effects of initial monomer and peroxide concentrations on the degree of grafting, on the amount of residual monomer, and on the side reactions were investigated. Reactive compatibilizers could be prepared with a suitable choice of processi...