The efficiency of cell-free protein synthesis combined with combinatorial selective 15N-labelling provides a method for the rapid assignment of 15N-HSQC cross-peaks to the 19 different non-proline amino-acid types from five 15N-HSQC spectra. This strategy was explored with two different constructs of the C-terminal domain V of the tau subunit of the Escherichia coli DNA polymerase III holoenzym...

Abstract: In this paper, the fifth order Improved Runge-Kutta method (IRK5) that uses just five function evaluations per step is developed. The method proposed here are derived with only five stages which results in lower number of function evaluations. Therefore, IRK5 has a lower computational cost than the classical fifth order Runge-Kutta method (RK5). Here, the order conditions of the metho...

Data communication networks have been experiencing tremendous growth in size, complexity, and heterogeneity over the last decade. This trend poses a significant challenge to the design of scalable performance evaluation methodologies. In this paper we propose time-stepped hybrid simulation (TSHS) to deal with the scalability issue faced by traditional packet level discrete event simulation meth...

A mutual evaluation system deals with a decision making problem including the feedback structure between alternatives and criteria. By incorporating decision makers’ intuitive judgments from alternatives to criteria into overall evaluations for alternatives, the mutual evaluation system may be effective to make a consensus among the decision makers of the problem. An analyzing tool of the mutua...

In this paper we present a differential semantics of Lazy AR Propagation (LARP) in discrete Bayesian networks. We describe how both single and multi dimensional partial derivatives of the evidence may easily be calculated from a junction tree in LARP equilibrium. We show that the simplicity of the calculations stems from the nature of LARP. Based on the differential semantics we describe how va...

We consider the problem of evaluating an appointment schedule for outpatients in a hospital. Given a fixed-length session during which a physician sees K patients, each patient has to be given an appointment time during this session in advance. When a patient arrives on its appointment, the consultations of the previous patients are either already finished or are still going on, which respectiv...

Schwartz, Bransford and Sears [1] propose a two-dimensional framework that describes transfer in terms of efficiency and innovation. Efficiency is the ability to apply prior knowledge to new situations quickly and accurately. Innovation is the ability to question assumptions, let go of prior knowledge and generate new ideas. Schwartz et. al. argue that most educational assessments focus on effi...

This paper reviews measurements of fission cross-sections of shortlived nuclear states, summarizes the formidable experimental difficulties involved and suggests novel methods of overcoming some of those difficulties. It is specifically concerned with the two such states that have been well characterized, the Jπ = 12 + (26 m) isomeric 235mU and the Jπ = 1− (16 h) ground state (shorter lived tha...

the performance evaluation and efficiency measurement of software companies and compare them together as a set of knowledge-based activities due to the unknown of internal processes and stages common to these companies and ignoring these processes in performance evaluation by data envelopment analysis models and how to consider these processes and procedures for calculating efficiency of each s...