background: protein aggregation is one of the important, common and troubling problems in biotechnology, pharmaceutical industries and amyloid-related disorders. methods: in the present study, the inhibitory effects of some carbohydrates (alginate, β-cyclodextrin and trehalose) on the formation of nano-globular aggregates from normal (hsa) and glycated (ghsa) human serum albumin were studied; w...

abstract arterial ischemic stroke defines as a new focal neurologic deficit that lasted 24 hours or longer. stroke is relatively rare in children and incidence of cerebrovascular disease is 1 per 4000 in neonates and 1 per 7000 to 1 per 70000 in older children (1 month to 18 years). protein s deficiency is one of the causes of the stroke in children. major manifestations of protein s deficiency...

background: interleukin-27 is a heterodimeric cytokine belonging to il-12 and il-23 families, secreted  by antigen presenting cells( apcs ) .the il-27 is composed of 2 subunits: epstein-barr virus induced gene 3 (ebi3) and p28. il-27 is an anti-inflammatory cytokine which has an inhibitory effect on th17 population and suppress the il-17 expression. it is suggested that il-27 could be a potent ...

white spot syndrome virus (wssv) is a highly pathogenic and prevalent virus affecting shrimp culture worldwide including iran. in the present study, a pair of primers was designed according to the sequence of vp 28 gene of wssv in the genbank. vp28 gene from an iranian wssv isolate (irvp28) was cloned, sequenced and expressed in escherichia coli bl21(de3) strain in order to produce vp28 protein...

for the purpose of increasing the permeability to oxygen and equilibrium water content in contact lenses, polar copolymers with nonionic monomers such as 2-hydroxyethle methacrylate(hema) is used. by adding the polar monomers to (hema), the permeability to oxygen and equilibrium with water content is increased and also the absorption of proteins on lens surface is changed. in this research, the...

how to cite this article: : farivar s, mohamadzade z, shiari r, fahimzad ar. neural differentiation of human umbilical cord mesenchymal stem cells by cerebrospinal fluid. . iran j child neurol. 2015 winter; 9(1):87-93.     abstract objective wharton’s jelly (wj) is the gelatinous connective tissue from the umbilical cord. it is composed of mesenchymal stem cells, collagen fibers, and proteoglyc...

conclusions the most common qnr gene was qnrb, and none of the isolates carried qnra or qepa. the aac (6’)-ib-cr variant was the most prevalent pmqr gene, and it was associated with the prevalence of ciprofloxacin resistance in our esbl-producing isolates. results of the 123 isolates, 103 (83.73%) had one of the five pmqr genes, including 83 (83.83%) of the 99 e. coli strains and 20 (86.95%) of...

conclusions the cell lines obtained in this work secreted potent, stable and specific anti-bv mabs, which were suitable for the development of herpes b virus diagnosis reagents. background herpes b virus (bv) is a zoonotic disease caused by double-stranded enveloped dna virus with cercopithecidae as its natural host. the mortality rate of infected people could be up to 70% with fatal encephalit...