PURPOSE To investigate the correlation between diabetic retinopathy severity and blood flow parameters in the central retinal artery (CRA) and internal carotid artery (ICA). METHODS This comparative study included 40 eyes of 20 patients with asymmetric diabetic retinopathy. Twelve subjects had asymmetric diabetic macular edema while eight patients had proliferative diabetic retinopathy (PDR) ...

BACKGROUND While glucocorticoids are currently the most effective therapy for asthma, associated side effects limit enthusiasm for their use. Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) activators include the synthetic thiazolidinediones (TZDs) which exhibit anti-inflammatory effects that suggest usefulness in diseases such as asthma. How the ability of TZDs to modulate the as...

Much evidence suggests that the positive association between meat intake and colorectal adenoma (CRA) and cancer (CRC) risk is mediated by mutagenic compounds generated during cooking at high temperature. A number of epidemiological studies have estimated the effect of meat-related mutagens intake on CRC/CRA risk with contradictory and sometimes inconsistent results. A literature search was car...

Critics of comparative risk assessment (CRA), the increasingly common practice of juxtaposing disparate risks for the purpose of declaring which one is the "larger" or the "more important," have long focused their concern on the difficulties in accommodating the qualitative differences among risks. To be sure, people may disagree vehemently about whether "larger" necessarily implies "more serio...

Bacteria are frequently faced with metabolic questions which, if answered appropriately, can enhance their reproductive and survival capabilities. They must decide how much of a specific nutrient they will take up and metabolize, which of the various equivalent nutrients that may be available they will select, and how they will respond to changes in relative nutrient concentrations as a functio...

BACKGROUND Few empirical studies longitudinally examine evidence-based practice (EBP) sustainment and the hypothesized factors that influence it. In an effort to address this gap, the current study examined sustainment of an EBP for adolescent substance use called the adolescent community reinforcement approach (A-CRA). METHODS A-CRA sustainment was assessed via information collected as part ...

We consider the following scheduling problem. There is a single machine and the jobs will arrive for completion online. Each job j is preemptive and, upon its arrival at time aj , its other characteristics are immediately revealed to the machine: the deadline dj , the workload Dj and the value vj . The objective is to maximize the aggregate value of jobs completed by their deadlines. Using the ...

As the main component for modern main memory system, DRAM stores data by capacitors, which must be refreshed periodically to keep the charges. As the size and speed of DRAM devices continue to increase, the overhead of refresh has caused a great power and performance dissipation. In this paper, we proposed a CAM (content-addressable memory)-based Retention-Aware DRAM (CRA-DRAM) system, a hardwa...

In this paper we examine the role of the classical pathway in the complement-mediated solubilization of immune precipitates (CRA). Serum reagents were depleted of the alternative pathway components properdin and factor D. Both depleted reagents lack CRA although they have almost intact hemolytic activity. Also, immune complexes were not solubilized when incubated with high concentrations of the...

We present spectro-astrometric observations for 28 southern pre-main sequence (PMS) stars and investigate their circumstellar environment down to AU scales. The structures detected in the “position spectra” include: (1) almost all the known binary companions in our sample (Sz 68, Sz 41, HO Lup, VW Cha, S CrA, AS 205), (2) companion candidates which have not been detected by infrared speckle tec...