In this paper, the size dependent behavior of the gold micro-switches has been studied. This behavior becomes noticeable for a structure when the characteristic size such as thickness or diameter is close to its internal length-scale parameter. The size dependent effect is insignificant for the high ratio of the characteristic size to the length-scale parameter, which is the case of the silicon...

Cytosolic compartmentalization through liquid-liquid unmixing, such as the formation of RNA granules, is involved in many cellular processes and might be used to regulate signal transduction. However, specific molecular mechanisms by which liquid-liquid unmixing and signal transduction are coupled remain unknown. Here, we show that during cellular stress the dual specificity kinase DYRK3 regula...

The benefits of the integration of novel optofluidic elements, e.g., fluidic lenses and liquid-core / liquid-cladding (L2) waveguides, for on-chip optical sample analysis are discussed. Using properly designed microfluidic channels, pre-calculated flow rate ratios and transparent fluids with different refractive indices but similar viscosity novel fluidic optical elements can be created. In thi...

The present investigation deals with the deformation in micropolar generalized thermoelastic medium with mass diffusion subjected to thermo mechanical loading due to thermal laser pulse. Laplace and Fourier transform technique is used to solve the problem. Concentrated normal force and thermal source are taken to illustrate the utility of approach. The closed form expressions of normal stress, ...

The aim of this study was to investigate the pharmacokinetic profiles of baicalin, wogonoside, baicalein and wogonin after oral administration of pure baicalin, Radix scutellariae and Scutellariae-Paeoniae couple extracts were administered and the pharmacokinetics profiles were compared between normal and ulcerative colitis rats. The plasma concentrations of the four flavonoids were determined ...