In general most of NSAIDs and cough suppressants are available as the over the counter drugs (OTC) without prescription. It has been believed that OTC drugs are relatively safe compared to prescription drugs, therefore, OTC drugs have been widely used for self-medication all over the world. However, the reports concerning to their drug-drug interactions are insufficient ...

OBJECTIVE It is a well known phenomenon in the Kingdom of Saudi Arabia that prescription drugs are dispensed over the counter in the community pharmacies. The aim of this study is to document the attitude of community pharmacists to fulfill the concept of pharmaceutical care and to evaluate how they manage a case of acute uncomplicated lower urinary tract infection. METHODS Eighty-eight commu...

Proton-pump inhibitors, PPIs, are widely prescribed and available over the counter for prolonged reduction of stomach acid production related disorders. PPIs irreversibly inhibit hydrogen/potassium ATPase in gastric parietal cells. Recent retrospective studies have described an association between PPI use depression. However, there is conflicting evidence that therapy improves depressive sympto...

This paper describes a new measure for presence in immersive virtual environments (VEs) based on data that can be obtained unobtrusively during the course of a VE experience. At different times during an experience a participant will occasionally switch between interpreting the totality of sensory inputs as forming the VE or the real world. The number of transitions from virtual to real is coun...

S. Pislak, P. Robmann and P. Tru ol, in collaboration with J. Egger, W. D. Herold, H. Kaspar, and H. Weyer, Paul{Scherrer{Institut, CH-5234 Villigen Brookhaven National Laboratory, Upton, NY-11973, USA University of New Mexico, Albuquerque, NM-87131, USA University of Pittsburgh, Pittsburgh, PA-15260, USA Yale University, Newhaven, CT-06511, USA Institute for Nuclear Research, Academy of Scien...

The ability to entrap drugs within vehicles and subsequently release them has led to new treatments for a number of diseases. Based on an associative phase separation and interfacial diffusion approach, we developed a way to prepare DNA gel particles without adding any kind of cross-linker or organic solvent. Among the various agents studied, cationic surfactants offered particularly efficient ...

BACKGROUND Over-the-counter medications are widely available in pharmacies Their safety profile, however, does not extend to pregnant women. Accordingly, there should be educational programs developed for pregnant women to protect them from the harms of the side effects. AIM This study was planned and designed with the aim of exploring the awareness and assessing the usage of OTC medications ...

Chromosomal loci containing genes affecting antinociceptive sensitivity to morphine have been identified, but virtually nothing is known about the genetic mediation of sensitivity to over-the-counter analgesics. Such knowledge would be of great clinical interest, as prodigious interindividual variability has been noted in the efficacy of these ubiquitously used drugs. In the present study, we a...

Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most widely used medications-both prescription and over the counter-in the United States. Gastrointestinal side effects from NSAIDs are responsible for significant patient morbidity and mortality as well as healthcare cost. With the development of cyclooxygenase-2 (COX-2) specific inhibitors, these serious adverse reactions have been s...