Although chemotherapy costs have not been highlighted traditionally, there is increasing pressure to demonstrate the value of new treatments within the health care budget. Pharmaceutical companies are assessing the economic value of their products before launch. Gemcitabine is a nucleoside analogue developed for use in solid tumours. The purpose of this model was to investigate the clinical out...

BACKGROUND Promoting bicycling has great potential to increase overall physical activity; however, significant uncertainty exists with regard to the amount and effectiveness of investment needed for infrastructure. The objective of this study is to assess how costs of Portland's past and planned investments in bicycling relate to health and other benefits. METHODS Costs of investment plans ar...

The corrosion protection factor (c.p.f.) and the corrosion condition (cc.) are simple instruments for the study and evaluation of the contribution and efficiency of several methods of corrosion prevention and control. The application of c.p.f. and cc. to corrosion and prevention in agriculture in The Netherlands is considered in detail. Attention is paid to relations between c.p.f. and c.c., th...

BACKGROUND AND PURPOSE Health economic analyses of intravenous tissue plasminogen activator (tPA) in acute ischemic stroke reveal a substantial cost savings. Unfortunately, tPA is vastly underused. The purpose of this study was to determine the economic impact of increasing tPA utilization in the United States. METHODS Annual incidence estimates of ischemic stroke in the United States and ind...