Magnetic resonance imaging (MRI) was used to evaluate within-subject variability in global mean cortical thickness over test-retest intervals of minutes-weeks in five healthy adults. Within-subject measures of global mean thickness were consistent over these intervals. Test-retest assessments of absolute thickness differences and percent thickness differences indicated variations of, respective...

Using finite element method (FEM), this study sought to investigate how the thickness and Young's modulus of cortical bone influenced stress distribution in bone surrounding a dental implant. The finite element implant-bone model consisted of a titanium abutment, a titanium fixture, a gold alloy retaining screw, cancellous bone, and cortical bone. The results showed that von Mises equivalent st...

BACKGROUND Whether there are differential effects of first-generation antipsychotics (FGAs) and second-generation antipsychotics (SGAs) on the brain is currently debated. Although some studies report that FGAs reduce grey matter more than SGAs, others do not, and research to date is limited by a focus on schizophrenia spectrum disorders. To address this limitation, this study investigated the e...

Cortical thickness estimation can provide clinically relevant information with respect to several neurodegenerative diseases, such as Alzheimer’s disease (Thompson et. al., 2004) and schizophrenia (Kuperberg et. al., 2003). Previously, most cortical thickness measurements have focused solely on grey matter (GM) thickness. Here, we present a method that allows, besides GM thickness, also the thi...

PURPOSE The purpose of this study was to obtain the description of the mandibular bone quality of male and female patients between 40-60 years old and their differences based on mandibular cortical bone thickness measured using Mental Index (MI). MATERIALS AND METHODS Forty digital panoramic radiographs, which consisted of twenty male and twenty female patients, 40-60 years old, were observed...

BACKGROUND/OBJECTIVE Migraineurs have atypical pain processing, increased expectations for pain, and hypervigilance for pain. Recent studies identified correlations between brain structure and pain sensation in healthy adults. The objective of this study was to compare cortical thickness-to-pain threshold correlations in migraineurs to healthy controls. We hypothesized that migraineurs would ha...

Adult cerebral cortical structure is thought to be statically maintained over short intervals. This view is based on group average findings but has never been studied at the individual level. This issue was examined with an unconventional longitudinal magnetic resonance imaging design which measured hemispheric mean cortical thickness of an adult man repeatedly at week intervals over 6 months. ...

The aim of this paper is to assess the heritability of cerebral cortex, based on measurements of grey matter (GM) thickness derived from structural MR images (sMRI). With data acquired from a large twin cohort (328 subjects), an automated method was used to estimate the cortical thickness, and EM-ICP surface registration algorithm was used to establish the correspondence of cortex across the po...

BACKGROUND People with schizophrenia may demonstrate cortical abnormalities, with gyri and sulci potentially being differentially affected. AIMS To measure frontal and temporal sulcal cortical thickness, surface area and volume in the non-psychotic relatives of patients with schizophrenia as a potential vulnerability indicator for the disorder. METHOD An automated parcellation method was us...

BACKGROUND Frontostriatal and frontoparietal abnormalities likely contribute to deficits in control and attentional processes in individuals with bulimia nervosa and to the persistence of dysregulated eating across development. This study assessed these processes and cortical thickness in a large sample of adolescent girls and women with bulimia nervosa compared with healthy controls. METHODS...