نتایج جستجو برای: cortical dysplasia

تعداد نتایج: 133004  

Journal: :Journal of child neurology 2009
Chihiro Sawai Tomoyuki Takano Yoshihiro Takeuchi

To examine the role of subventricular zone in cortical dysplasia, an experimental model was established using a neuronal tracing study. Ibotenate is a glutamate receptor agonist, and its intracerebral injection produces excitotoxic lesions mimicking microgyria and heterotopia. A total of 72 newborn hamsters were subjected. Biotinylated dextran amine was injected into the ganglionic eminence for...

C.C. Chang, C.C. Hsu, C.Y. Lin, Y.C. Tyan, Y.F. Huang, Y.M.A. Chen, Y.W. Chuang,

Background: Melorheostosis has been discussed infrequently in the nuclear medicine literature. A 25-year-old female patient presented with a one-year history of b:union: pain, sclerotic change and skin pigmentation on the left big toe interphalangeal joint. Ulceration, poor healing and hyperkeratoses of the wound were noted post debridement. The plain film of the left foot incidentally showed m...

Journal: :Neurology 2000
S P Miller M I Shevell Y Patenaude C Poulin A M O'Gorman

The authors describe three children with septo-optic dysplasia (SOD)-plus: SOD and an associated malformation of cortical development. All three children had developmental delay, and two of the children had significant associated motor deficits. The associated cortical malformations with SOD include a spectrum of disorders of neuronal organization, not limited, as previously described, to schiz...

2015
Tomokazu Kimizu Hiromitsu Toshikawa Sadami Kimura Tae Ikeda Yukiko Mogami Keiko Yanagihara Haruhiko Kishima Yasuhiro Suzuki

Ictal bradycardia, which is considered to be one of the causes of sudden unexplained death in epilepsy, is rare. A 10-year-old girl with focal cortical dysplasia in her right centroparietal region developed transient ictal bradycardia during cluster seizures. Brain magnetic resonance imaging demonstrated a high signal intensity lesion adjacent to the focal cortical dysplasia lesion. Ictal 99mTc...

Journal: :Epileptic disorders : international epilepsy journal with videotape 2008
Lara E Jehi Hans O Lüders Richard Naugle Paul Ruggieri Harold Morris Nancy Foldvary Elaine Wyllie Prakash Kotagal Bill Bingaman Dudley Dinner Richard Prayson Beate Diehl Andreas Alexopoulos Jocelyn Bautista Robyn Busch

[March 2008-Cleveland Case Report]. There is a well-described association between the occurrence of developmental tumors and the presence of cortical dysplasia in the neighboring brain tissue. The main surgical approaches in the treatment of medically refractory epilepsy related to such developmental tumors include a lesionectomy versus a tailored cortical resection, often guided by an invasive...

2008
Lara E. Jehi Richard Naugle Paul Ruggieri Elaine Wyllie Richard Prayson Andreas Alexopoulos Robyn Busch

[March 2008 Cleveland Case Report]. There is a well-described association between the occurrence of developmental tumors and the presence of cortical dysplasia in the neighboring brain tissue. The main surgical approaches in the treatment of medically refractory epilepsy related to such developmental tumors include a lesionectomy versus a tailored cortical resection, often guided by an invasive...

2017
Kevin M. Sweet Dennis W.W. Shaw Teresa Chapman

A 7-year-old boy with a history of spasticity, global developmental delay, and seizures was given the general diagnosis of cerebral palsy at an early age. Chromosomal array analysis performed at an outside center was normal. The patient's family sought neurodevelopmental pediatric care at a new institution following a move out of state. Electroencephalography confirmed abnormal epileptogenic ac...

2017
Tim J. Veersema Cyrille H. Ferrier Pieter van Eijsden Peter H. Gosselaar Eleonora Aronica Fredy Visser Jaco M. Zwanenburg Gerard A. P. de Kort Jeroen Hendrikse Peter R. Luijten Kees P. J. Braun

Objective The aim of this study is to determine whether the use of 7 tesla (T) MRI in clinical practice leads to higher detection rates of focal cortical dysplasias in possible candidates for epilepsy surgery. Methods In our center patients are referred for 7 T MRI if lesional focal epilepsy is suspected, but no abnormalities are detected at one or more previous, sufficient-quality lower-fiel...

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