AIMS Although hirudin is superior to unfractionated heparin for prevention of death, myocardial infarction, or refractory ischaemia in patients with non-ST-elevation acute coronary syndrome, it is not clear whether hirudin is also of benefit in acute coronary syndrome patients undergoing early percutaneous coronary intervention. METHODS AND RESULTS In the OASIS 2 trial, 10 141 patients with n...

Allergic reaction-associated acute coronary syndrome picture is defined as Kounis syndrome. Although drug use is the most common cause of allergic reaction, foods and environmental factors may also play a role in the etiology. Herein, a case with acute coronary syndrome that developed two times at 8-month interval due to pseudoephedrine use for upper respiratory tract infection is presented.

Background: Cardiovascular diseases are global problems. They are causes of death in about 43% of people worldwide and may become the most widespread reason of death by 2020. The prognosis is directly dependent to immediate diagnosis and on time treatment. Introduction of new biochemical markers as the early diagnosis of complications after coronary revascularization is very important in this p...

Percutaneous coronary intervention (PCI) is a safe and effective procedure to reconstitute myocardial perfusion and has been demonstrated to improve prognosis in patients with acute coronary syndrome. With advancing age, PCI carries a higher risk for acute coronary and other vascular complications. Periprocedural mortality risk after PCI demonstrates a curvilinear relationship with age, with th...

Introduction Takotsubo Cardiomyopathy (CT), also known as stress-induced cardiomyopathy, is a reversible syndrome that usually presents an acute coronary syndrome, especially in postmenopausal women. The pathophysiology involves multiple factors, including vasospasm, microcirculation dysfunction, catecholaminergic aggression, and sympathetic hyperactivity. diagnosis of the classic presentation ...

Kounis syndrome is an allergy-associated acute coronary syndrome, which develops secondary to mast cell activation in coronary arteries due to hypersensitivity or anaphylactoid reaction (1). The triggering factors may be various drugs, food, environmental exposure, and intracoronary stents (2–4). In this case report, an extraordinary case of Kounis syndrome (acute myocardial infarction with con...

The COVID-19 pandemic severely disrupted cardiovascular care during the spring of 2020 in Europe. Our study analyzed clinical profile, impact, and 30-day prognosis invasively managed patients with acute coronary syndrome (ACS) compared to a historical cohort.