PURPOSE To report the observation of a triple corneal dystrophy association consisting of keratoconus (KC), epithelial basement membrane corneal dystrophy (EBMCD) and Fuchs' endothelial corneal dystrophy (FECD). METHODS A 55-year-old male patient was referred to our cornea service for blurred vision and recurrent foreign body sensation. He reported bilateral recurrent corneal erosions with di...

Corneal curvature (CC) measures the steepness of the cornea and is an important parameter for clinically diseases such as astigmatism and myopia. Despite the high heritability of CC, only two associated genes have been discovered to date. We performed a three-stage genome-wide association study meta-analysis in 12 660 Asian individuals. Our Stage 1 was done in multiethnic cohorts comprising 744...

PURPOSE To evaluate the impact of differente soft contact lens power in the anterior corneal curvature and regularity in subjects with keratoconus. METHODS Nineteen subjects (30 eyes) with keratoconus were included in the study. Six corneal topographies were taken with Pentacam Eye System over the naked eye and successively with soft lens (Senofilcon A) powers of -3.00, -1.50, 0.00, +1.50 and...

PURPOSE To assess the intraocular pressure (IOP) and its association in children in a population living in an oasis in the Gobi Desert. METHODS The cross-sectional school-based study included all schools in the Ejina region. The children underwent an ophthalmic examination, non-contact tonometry and measurement of blood pressure and body height and weight. RESULTS Out of eligible 1911 child...

Keratoconus is a progressive corneal thinning of unknown cause in which the cornea assumes a conical shape, with progressive irregular astigmatism and deterioration of visual acuity. The normal anterior corneal surface is prolate, and it could be described as conic (flattening of the radius of curvature from the apex toward the periphery)1. In keratoconus corneas, the steepening of the central ...

OBJECTIVE To investigate the fluctuations in intraocular pressure during the day and to see if these are associated with changes in corneal shape and in the patterns of ocular aberrations. METHODS Intraocular pressure, corneal curvature, refractive error, spherical equivalent and aberrations (defocus (sphere); cylinder (astigmatism); coma, trefoil and third order spherical aberration) were me...

Purpose To study the variations in corneal clinical biomechanical parameters (CCBP) and corneal geometrical parameters of rabbit in relation to age. Methods Rabbits aged 3, 7, 12, 18, and 24 months were enrolled. Each eye of the rabbits was tested with Ocular Response Analyzer (ORA), Optical Coherence Tomography (OCT), and Pachymeter to obtain the intraocular pressure (IOP): Goldmann-correlat...

Methods: Patient records were identified from a specialty contact lens practice. Data were obtained from myopic patients who were prescribed Ortho-K wear. Demographic data at baseline included age at commencement of Ortho-K and ethnicity. Clinical data recorded at baseline and at years 1, 2 and 3 included subjective refraction, corneal topography, corneal curvature, axial length, pupil size, an...

CASE REPORT We report the case of a 34 year-old man with progressive loss of visual acuity in his left eye, who was diagnosed with pigmentary glaucoma with an intraocular pressure of 32mmHg. Eight years previously, the patient had undergone refractive surgery (LASIK). Hypotensive treatment led to a significant refractive change accompanied by flattening of the corneal curvature. DISCUSSION We...

PURPOSE To investigate the topography of the central and peripheral cornea in a group of young adult subjects with a range of normal refractive errors. METHODS Corneal topography data were acquired for 100 young adult subjects by a method that allows central and peripheral maps to be combined to produce one large, extended corneal topography map. This computer-based method involves matching t...