This Interventional case reports a challenging case of descemet's stripping-automated endothelial keratoplasty (DSAEK) in a young male patient with traumatic aniridia, aphakia, and corneal edema. Surgery was planned in two stages; first was implantation of aniridia intraocular lens (AIOL), few months later, DSAEK procedure was performed. Successful outcome of both procedures was achieved as mea...

PURPOSE Refractive and visual analysis in corneal transplantations performed for keratoconus by two groups of surgeons. METHODS Seventy eyes of seventy patients, which had been submitted to penetrating keratoplasty (PK) for keratoconus, were examined and their charts were reviewed retrospectively for long-term results after all sutures had been removed. The patients were divided into two grou...

PURPOSE To characterize the presence of plasminogen activators and their inhibitors in the corneas during the inflammatory response in naïve and immunized mice intracorneally infected with Pseudomonas aeruginosa. METHODS RT-PCR was used to detect gene expression for plasminogen activators and their inhibitors in naïve and immunized mice. Immunoblot analysis, zymography, and ELISA were used to...

PURPOSE To report the outcomes of allograft limbal stem cell transplantation for recurrent gelatinous drop-like corneal dystrophy (GDLD). METHODS In this non-comparative interventional case series, 4 eyes of 3 consecutive patients with recurrent GDLD underwent allograft limbal stem cell transplantation. Two eyes underwent concomitant penetrating keratoplasty while the other two underwent simu...

PURPOSE The purpose of this study was to evaluate sutureless keratoplasty using a chemically-defined bioadhesive (CDB) made from food or medical additives. METHODS Sutureless automated lamellar therapeutic keratoplasty (ALTK) using a CDB was performed on three rabbit eyes. Allogenic lamellar graft was transplanted onto the recipient bed using either suture fixation or a sutureless technique u...

PURPOSE To determine the clinical outcomes of simultaneous penetrating keratoplasty (PK), cataract removal and intraocular lens implantation (triple procedure), and to compare the safety and efficacy of two different cataract extraction techniques during the course of PK. METHODS This retrospective comparative study was conducted on patients who had undergone a triple procedure. The technique...

Detailed examinations were conducted on 162 consecutive children with nutritional keratopathy. Surface changes ranged from mild haziness through generalized xerosis and formation of thickened keratinized plaques. Diffuse stromal edema occured early in the disease. Stromal loss took two forms: relatively small, sharply demarcated, eccentric, noninfiltrated cylindrical ulcers of varying depth; an...

In situ gelling systems are becoming one of the most popular and well-known, with many potential benefits from delivery systems, such as ease use manufacture, improve adherence patient comfort by minimizing frequency drug administration. this review, we will describe characterization evaluation ophthalmic in gel preparation. Among them physical (appearance clarity, pH, isotonicity, gelation tem...

Background: Ocular chemical burns induce devastating and permanent damage to the ocular surface. Rapid intervention is required for maximal visual rehabilitation. Amniotic membrane transplantation (AMT) may save the ocular surface, however it introduces a potentially unnecessary surgical trauma in such compromised eyes. Amniotic membrane extracts (AME) could be a practical substitute of AMT in ...

OBJECTIVE To describe the authors' experience using keratoprosthesis to treat pediatric corneal opacity. DESIGN Nonrandomized, consecutive, retrospective interventional series. PARTICIPANTS Twenty-two eyes of 17 children with opaque corneas as a result of primary congenital disease and or previous failed keratoplasty. METHODS A retrospective review of pediatric patients with a history of ...