OBJECTIVE To evaluate umbilical cord abnormalities predisposing to mechanical cord compression and determine their relationship to adverse clinical outcomes and stasis-associated histologic changes in the placenta. METHODS Placental slides of 224 singleton pregnancies with gross cord abnormality (true knots, long cords, nuchal/body cords, abnormal cord insertion, hypercoiled cords, narrow cor...

OBJECTIVE To characterize and compare the MRI morphological features of the cervical vertebral column of Great Danes with and without clinical signs of cervical spondylomyelopathy (CSM). DESIGN Prospective cohort study. ANIMALS 30 Great Danes (15 clinically normal and 15 CSM-affected). PROCEDURES All dogs underwent MRI of the cervical vertebral column (C2-3 through T1-2). Features evaluat...

Metastatic Epidural Spinal Cord Compression The axial skeleton is a commonly involved site in patients with bone metastases. Progressive spinal metastasis may result in epidural spinal cord compression, and lead to paresis and paralysis if left untreated [1-3]. The treatment of metastatic epidural spinal cord compression is determined by disease factors such as histology, site of disease, exten...

The syndrome of pseudohypoparathyroidism describedbyAlbright, Burnett, Smith, andParson (1942) has been well reviewed by MacGregor andWhitehead (1954) and by Mann, Alterman, and Gorman Hills (1962). The clinical features consist of mental retardation, epilepsy and attacks of tetany, as well as ectodermal defects such as alopecia, defective dentition, brittlenails, andcataracts. There are also c...

BACKGROUND AND PURPOSE The criteria for selecting patients who may benefit from surgery of spinal cord compression in metastatic prostate cancer are poorly defined. We therefore studied patients operated for metastatic spinal cord compression in order to evaluate outcome of surgery and to find predictors of survival. PATIENTS AND METHODS We reviewed the records of 54 consecutive patients with...

The spinal cord extends from the base of the skull and terminates near the lower margin of the L1 vertebral body. Below L1, the spinal canal contains the lumbar, sacral and coccygeal spinal nerves that comprise the cauda equina. Therefore, injuries below L1 involve the segmental spinal nerves and/or cauda equina. Injuries above the termination of the spinal cord at L1 often involve both spinal ...

Forty-six dogs with either cervical (C1-C5 or C6-T2) or thoracolumbar (T3-L3) acute myelopathy underwent prospective conventional computed tomography (CT), angiographic CT, myelography, and CT myelography. Findings were confirmed at either surgery or necropsy. Seventy-eight percent of lesions were extradural, 11% were extradural with an intramedullary abnormality, 7% were intramedullary, 2% wer...

Herniated thoracic intervertebral disk causing spinal cord compression with paraparesis is uncommon in adults and rare in children. This article describes a case of pediatric thoracic disk herniation with paraparesis treated surgically.A 14-year-old girl presented with a 4-month history of diffuse back pain and sudden onset paraparesis. Motor strength was 4/5 in both legs, and she had lost the ...

BACKGROUND Diffuse idiopathic skeletal hyperostosis has long been regarded as a benign asymptomatic clinical entity with an innocuous clinical course. Neurological complications are rare in diffuse idiopathic skeletal hyperostosis. However, if they do occur, the consequences are often significant enough to warrant major neurosurgical intervention. Neurological complications occur when the patho...

Arachnoid web is a rare disease entity that can cause progressive myelopathy and most often develops at the upper thoracic level. Its pathophysiology unclear, but may be associated with degeneration of septum posticum in dorsal subarachnoid space, which alters flow cerebrospinal fluid (CSF) subsequently leads to cord compression syringomyelia. It presents pain, paresthesia, extremity weakness. ...