spinal cord injury (sci) is one of the devastating conditions leading to functional and neurological deficits following road traffic accidents. to date, there is no definite treatment for repairing damaged spinal cord tissue. in this regard, cell therapy opens a new window in front of scientists by using different cells such as mesenchymal stem cells, olfactory ensheathing cells, schwann cells,...

Background: The application of mesenchymal stem cells in the healing of chronic wounds is one of the most challenging issues in cell therapy. The present study investigated the efficacy of intradermal injection of umbilical cord Wharton's Jelly-derived mesenchymal stem cells in diabetic wound healing using ultrasound imaging in an animal model. Methods: During this experimental laboratory stud...

Umbilical cord blood is an acceptable source of hematopoietic stem cells for patients with malignant diseases but has limitations in its use. In this review, we will discuss these limitations and the recent advances in cord blood transplants that may enable cord blood to become more widely available as an alternative stem cell source for adults for the treatment of malignant diseases and for us...

HCTHematopoietic cell transplantation (HCT) refers to a procedure in which hematopoietic stem cells are infused to restore bone marrow function in cancer patients who receive bone-marrowtoxic doses of cytotoxic drugs, with or without whole-body radiation therapy. Hematopoietic stem cells may be obtained from the transplant recipient (autologous HCT) or from a donor (allogeneic HCT). They can be...

The stem cells, derived from the cord blood are hematopoietic cells. These have immense potential in curing related disorders like cancers, thalassemia etc. can be useful treating tissue of heart, bone, spinal Stem cells characterized by ability to renew through mitotic cell division and differentiate into a diverse range specialized types. Cells basic building blocks body replenish other give ...

This issue of STEM CELLS Translational Medicine marks an important milestone in the journal’s mission to advance the clinical use of stem cells. Through a partnership with the Cord Blood Association, SCTM now includes a new section to showcase the newest and highest quality translational and clinical applications of cord blood and cord tissue-based therapies. Areas the new section will focus on...