Pentoxifylline, an inhibitor of cAMP phosphodiesterase activity, favours intracellular cAMP concentration increase. In-vitro treatment of semen with pentoxifylline leads to marked augmentation of sperm motility, enhancement of acrosome reaction, increase of sperm penetration into zona-free hamster oocytes, and protection of the sperm plasma membrane. Such properties indicate that the drug may b...

BACKGROUND The purpose of this study was to evaluate the prognostic effect of Hyaluronan Binding Assay (HBA) which has been used as a method of sperm selection for intracytoplasmic sperm injection procedure, on the outcome of intrauterine insemination (IUI) in couples with unexplained or mild male factor infertility. METHODS 77 infertile couples were enrolled in our study. On the day of IUI p...

OBJECTIVES To evaluate the incidence of functional and chromatin alterations on spermatozoids in patients grouped according to normality of standard semen parameters based on the 5th edition of the World Health Organization (WHO) guidelines. To identify and correlate the most frequently altered characteristics in the normal standard semen parameters sub-population. MATERIALS AND METHODS A pro...

male urogenital tract infection plays an important role in men infertility. asymptomatic bacteriospermia has been paid attention as a major cause of male infertility. the aim of this study was to microbiological investigation of semen sample of infertile men attending to infertility clinic and evaluation of the effects of bacteriospermia on semen quality. eighty eight infertile men were evaluat...

OBJECTIVE To evaluate ejaculated spermatozoa from patients with male factor infertility for the role of cytochrome c and caspases 9 and 3 (the proteins known to mediate apoptosis) and to examine association between semen quality and apoptosis in the presence of oxidative stress. DESIGN Prospective study. SETTING Male infertility clinic at a tertiary health care center. PATIENT(S) Semen sp...

Varicocele is a common condition amongst infertile men. repair (VR) frequently performed to improve semen quality, sperm DNA fragmentation, and the chances of pregnancy. However, there lack consensus about diagnosis, indications, outcomes for VR. The aim this study was explore global practice patterns practicing male infertility clinicians on management varicocele in context couple infertility.

OBJECTIVE The aim of this study is to investigate the various causes of male infertility using multiple approaches. METHODS Nine-hundred-twenty infertile male patients were analyzed at their first visit with one physician between January 1 and December 31, 2009. All patients were subjected to physical examination, semen analysis and azoospermic patients underwent hormonal testing, chromosomal...

Background: With the introduction of COVID-19 vaccines in 2021, concerns arose regarding their impact on male fertility. Therefore, this study investigated effect mRNA- and vector-based vaccination fertility by analyzing sperm parameters subjects with unrestricted restricted Methods: In prospective self before-after control at a single University-based Infertility Center Duesseldorf, Germany, t...

The objective of this review was to summarize the evidence concerning the benefit of varicocele treatment to improve natural fertility in subfertile males. We also analyzed the effect of varicocele treatment on conventional semen parameters and sperm functional tests. An electronic search to collect the data was performed using the PubMed/MEDLINE databases until July 2015. Data pooled from a va...

Introduction: There is not enough evidence regarding the influence of folate deficiency in etiology idiopathic male infertility. Objectives: The objective current study was to examine whether there an association between serum levels and sperm parameters among infertile males. Patients Methods: This cross-sectional undertaken on a sample males referring infertility treatment clinic Isfahan prov...