Introduction The practice of clinical diagnostic radiology has been made possible by advances not only in diagnostic equipment and investigative techniques, but also in the contrast media that permit visualisation of the details of the internal structure or organs that would not otherwise be demonstrable. The remarkably high tolerance of modern contrast media has been achieved through successiv...

Cross-use of technology between nuclear medicine and radiology technologists is expanding. The growth of PET/CT and the increasing use of intravenous contrast agents during these procedures bring the nuclear medicine technologist into direct contact with these agents and their associated complications. A basic understanding of the occurrence, risk factors, clinical features, and management of t...

BACKGROUND This systematic review combines data from multiple papers on contrast media extravasation to identify factors contributing to increased extravasation risk. METHODS Data were extracted from 17 papers reporting 2191 extravasations in 1,104,872 patients (0.2%) undergoing computed tomography (CT) or magnetic resonance imaging (MRI). RESULTS Extravasation rates were 0.045% for gadolin...

Radiographic contrast agents have been in use for over 60 years to improve the visibility of internal organs and structures in X-ray based imaging techniques such as radiography, angiography, and contrast-enhanced computed tomography scans and to perform cardiac catheterizations and percu-taneous coronary interventions. Their use for imaging and intravascular intervention keeps increasing parti...

Increasing use is made of extracellular MRI contrast agents that alter the image contrast following intravenous administration; they predominantly shorten the T1 relaxation time of tissues. The degree and location of these changes provide substantial diagnostic information. However gadolinium-based contrast agents (Gd-CA) are not inert drugs. They may cause acute non-renal adverse reactions (e....

Intravenous contrast agents are frequent adjuncts used in diagnostic imaging. Despite the well-recognized complications of contrast media extravasation, its treatment remains an enigma to many. This article reviews the recognition, prevention and treatment options, with a summary of the contrast media extravasation policy implemented in our department.

A 60-year-old man who had previous coronary artery bypass graft surgery with a left internal mammary artery (LIMA) graft, underwent a coronary angiogram to investigate multiple episodes of angina. His only other significant past medical history was well-controlled hypertension. The patient was previously exposed to iodinated contrast media with no history of reaction. His pre-procedural blood p...

*Corresponding author: Majid Tavafi, Department of anatomy, Faculty of Medicine, Lorestan University of Medical sciences, Khoram Abad, Iran. E-mail: [email protected] Radiological procedures using injection of contrast media have been employed increasingly for diagnostic purposes (1). Nevertheless, side effect of contrast media injection known as contrast media nephrotoxicity is still a major c...

Contrast-induced nephropathy is a common cause of acute renal failure, and the mechanisms underlying this injury are not completely understood. We sought to determine how physicochemical properties of contrast media may contribute to kidney damage in rats. We administered contrast media of equivalent iodine concentrations but differing physiocochemical properties: the high-osmolality iopromide ...