FOCAL neurological defects due to stenosis or occlusion within the main arterial trunks feeding the brain have become recognized with increasing frequency in recent years. However, until recently, knowledge concerning the effects of occlusion of the internal carotid artery has outstripped that of occlusion within the vertebral-basilar artery system. Both commonly produce ophthalmological featur...

Stroke typically occurs in elderly people with a range of comorbidities including carotid (or other arterial) atherosclerosis, high blood pressure, obesity and diabetes. Accordingly, when evaluating therapies for stroke in animals, it is important to select a model with excellent face validity. Ischemic stroke accounts for 80% of all strokes, and the majority of these occur in the territory of ...

OBJECTIVE To assess the early results of combined coronary artery bypass graft surgery and carotid endarterectomy. DESIGN Retrospective and ongoing analysis of patients who underwent combined coronary artery bypass graft surgery and carotid endarterectomy. SETTING Cardiothoracic unit in a London teaching hospital. PATIENTS From June 1987 to March 1995, 64 patients were identified. They we...

OBJECTIVE To identify risk factors for operative stroke and death from carotid endarterectomy. DESIGN Systematic review of all studies published since 1980 which related risk of stroke and death to various preoperative clinical and angiographic characteristics, including unpublished data on 1729 patients from the European carotid surgery trial. MAIN OUTCOME MEASURE Operative risk of stroke ...

This study aimed to compare the clinical value of carotid ultrasound and digital subtraction angiography (DSA) for artery stenosis in patients with cerebral infarction. Sixty infarction underwent DSA. Carotid stenosis, degree (mild, moderate, severe, occlusion), plaques were recorded compared. rate was 96.67 % (58/60) 91.67 (55/60) on DSA ultrasound, respectively, difference not statistically s...

We retrospectively studied 46 patients with symptomatic retinal artery occlusion and assessed the pattern and extent of carotid artery disease ipsilateral to the retinal artery occlusion. Ipsilateral internal carotid artery atherosclerotic lesions were virtually limited to the cervical arterial segment; 50% of such lesions were plaques or stenoses of less than or equal to 60%, whereas 15% of th...