Usefulness of the Brief Psychiatric Rating Scale (BPRS) in distinguishing positive and negative subtypes of schizophrenia is presented. Ninety five schizophrenic patients were assessed on BPRS. Significant differences emerged between positive and negative subtypes of schizophrenia on items like emotional withdrawal, guilt feelings, tension, hallucinatory behaviour, motor retardation, blunted af...

It is recognized that neuropsychiatric conditions are overrepresented in amyotrophic lateral sclerosis (ALS) patient kindreds and psychiatric symptoms may precede the onset of motor symptoms. Using a hospital record linkage database, hospitalization with a diagnosis of schizophrenia, bipolar disorder, depression, or anxiety was significantly associated with a first diagnosis of ALS within the f...

This study examined affect perception in schizophrenia. Subjects were 35 patients with schizophrenia or schizoaffective disorder, 11 with bipolar disorder, and 19 matched nonpatient controls. All patients were in the latter stages of an acute hospitalization. Measures included a videotaped test of affect perception administered with and without sound, two tests of facial affect perception based...

BACKGROUND Schizophrenia is a chronic disease that requires long-term management with antipsychotics; however, an important barrier to the success of long-term treatment is drug noncompliance, which increases the risk of recurrence and hospitalization. Second-generation long-acting injectable antipsychotics have improved drug adherence, and the pharmacological effects of the drugs, and therefor...

Individuals with lower socio-economic status (SES) are at increased risk of physical and mental illnesses and tend to die at an earlier age [1-3]. Explanations for the association between SES and health typically focus on factors that are environmental in origin [4]. However, common SNPs have been found collectively to explain around 18% of the phenotypic variance of an area-based social depriv...

Background: Medication non-adherence is a major reason for poor outcomes in schizophrenia. Long-acting injectable (LAI) risperidone microspheres, the first LAI second generation antipsychotic (SGA), may improve adherence and thereby outcomes, but has not been tested in a long-term randomized trial of unstable patients, against flexibly prescribed oral treatment. Methods: Patients with schizophr...

Introduction Home Treatment (HT) teams are among the better-studied options to reduce admission at hospital, having been described as an alternative hospitalization in patients with schizophrenia. There may be certain risk factors which has already such living alone (Dean and Gadd, BMJ, 1990; 301, 1021–1023; Schnyder et al., Acta Psychiatr. Scand. 1999; 99, 179–187), lack of awareness illness, ...

Introduction: A number of research studies have shown that the new generation of neuroleptic medications can more effectively contribute to treating negative symptoms of schizophrenia compared with the first generation by influence cognitive functioning. The present study examined the therapeutic effectiveness of manufactured Risperidone and Haloperidol in Iran on treating the negative symptoms...