Adrenocortical hyperplasia is uncommon in childhood. It occurs as the adrenogenital syndrome (congenital virilism in girls) which has now been shown to be due to a congenital defect in the synthesis of cortisol by the adrenal cortex. In the United States its incidence is once in every 58,000 live births (Grumbach, 1956) and it has a recessive mode of inheritance. The disease is more easily diag...