INTRODUCTION Congenital cholesteatoma is thought to be caused by inadequate folding of the epidermoid formation inside the middle ear cleft. During development of the middle ear mucosa, stratified squamous epithelium accumulates in the embryonic life. Its typical appearance is a "pearl" beneath the anterosuperior quadrant of the tympanic membrane. PRESENTATION OF CASE We report 28 years-old c...

Hearing loss is one of the common congenital problems among neonates [1]. The prevalence of significant hearing loss ranges from 1.2 per 1,000 healthy newborn infants and 2 to 5% in high-risk newborns [2,3]. Nearly 50% of congenital hearing loss is due to genetic defects [1]. About 50% of hearing defects can be detected in a selective screening based exclusively on hearing risk criteria [1]. Ea...

As regards the significant role of stethoscopes in the diagnosis of congenital and adventitious heart diseases and prevention of irreparable complications of these diseases, the quality of hearing sound of these stethoscopes by a physician has a significant impact on the disease diagnosis. This device plays an important role in the early diagnosis of congenital heart and respiratory diseases an...

Cognitive Hearing Science or Auditory Cognitive Science is an emerging field of interdisciplinary research concerning the interactions between hearing and cognition. It follows a trend over the last half century for interdisciplinary fields to develop, beginning with Neuroscience, then Cognitive Science, then Cognitive Neuroscience, and then Cognitive Vision Science. A common theme is that an i...

Universal newborn hearing screening (UNHS) was begun in the United States in several geographic locations, the states of Rhode Island, Hawaii, and Colorado in the early 1990s. Since that time, evidence-based research indicates that universal newborn hearing screening results in earlier identification of congenital hearing loss leading to the provision of earlier intervention. Outcome data of ch...

Abstract Contemporary digital in ear hearing aids are of significant importance for social participation users with impairments. Through the advancement technology, extreme miniaturisation these devices has been achieved. However, by no means all people who could benefit from a aid actually use one. Cormack and Fortnum state that majority (80%) adults aged 55–74 years would aid, do not them. Th...

OBJECTIVES To investigate the validity of newborn hearing screening protocol using automated auditory brainstem response (AABR) with a confirmation method using click auditory brainstem response (ABR) and to evaluate changes in hearing status of infants with confirmed congenital hearing loss. METHODS Neonates in the well-baby nursery were screened by staged AABR. Subjects whose final AABR res...

OBJECTIVES To assess whether a classification system for congenital cholesteatoma (CC) can be derived from analysis of a large clinical sample of cases and to assess whether such a classification system is a reliable guide for surgical intervention, reexploration, and hearing outcome. DESIGN A retrospective review of clinical and surgical records of 119 patients with CC. SETTING Four tertia...

CONTEXT Mutations in the GJB2 gene are the most common known cause of inherited congenital severe-to-profound deafness. The carrier frequency of these mutations is not known. OBJECTIVES To determine the carrier rate of deafness-causing mutations in GJB2 in the midwestern United States and the prevalence of these mutations in persons with congenital sensorineural hearing loss ranging in severi...

Congenital human cytomegalovirus (HCMV) occurs in 0.5-1% of live births and approximately 10% of infected infants develop hearing loss. The mechanism(s) of hearing loss remain unknown. We developed a murine model of CMV induced hearing loss in which murine cytomegalovirus (MCMV) infection of newborn mice leads to hematogenous spread of virus to the inner ear, induction of inflammatory responses...