Relapsing polychondritis (RPC) is a unique and rarely observed autoimmune condition regarded as recurrent extensive chondritis of the auricular, nasal, and tracheal cartilages. Moreover, heart, main arteries, skin, and eyes may be involved. Several forms of clinical manifestations may be seen, and the pathogenesis still remains anonymous. A concomitant disease, particularly myelodysplasia or ot...

Two contradictory hypotheses on the role of dietary carbohydrates in health and disease shape how dental-systemic associations are regarded. On one side, Cleave and Yudkin postulated that excessive dietary fermentable carbohydrate intake led-in the absence of dental interventions such as fluorides-first to dental diseases and then to systemic diseases. Under this hypothesis, dental and systemic...

The homeostasis of neutrophil granulocytes can affect the outcome of several inflammation-associated diseases including cancer. The regulation of this homeostasis is still not completely understood. We previously found that elevated systemic levels of tissue inhibitor of metalloproteinases-1 (TIMP-1) induce an increase of neutrophils in the liver, which in turn strongly promotes liver metastasi...

Introduction: The atopic march consists of dermatitis (AD), allergic rhinitis or sinusitis (AR), conjunctivitis (AC) and bronchial asthma (BA). influence concomitant diseases on AD is under-explored. We determined the relationship between personal family history with severity persistence. Methods: A cross sectional study involving patients was performed at dermatology clinics two tertiary hospi...

У здоровой женщины при нормально протекающей беременности структурно-функциональные изменения сердца носят адаптивный характер, выражены незначительно и полностью нормализуются после родов. беременной с теми или иными заболеваниями адаптационные возможности снижены, поэтому на любом этапе могут возникать патологические изменения, осложняющие ее течение приводящие к неблагоприятным исходам. Кром...

Introduction. In recent years, more and attention has been paid to the study of relationship between inflammatory processes in periodontium somatic diseases. Systemic processes, particular, dystrophic lesions spine are known have a significant role, leading profound changes internal environment body structural periodontal tissues. The peculiarities clinical course disease patients with predomin...