In skeletal muscle, an increased expression of insulin like growth factor-I isoforms IGF-IEa and mechano-growth factor (MGF) combined with downregulation of myostatin is thought to be essential for training-induced hypertrophy. However, the specific effects of different contraction types on regulation of these factors in muscle are still unclear, and in tendon the functions of myostatin, IGF-IE...

OBJECTIVE To investigate the possible electrophysiological background of the greater excitability of concentric and eccentric left ventricular hypertrophy types in relation to the asymmetric type. METHODS 187 patients with essential hypertension, without ishaemic heart disease were divided into three groups with regard to left ventricule type: concentric (relative wall thickness >0.42, interv...

RATIONALE An increase in cardiac afterload typically produces concentric hypertrophy characterized by an increase in cardiomyocyte width, whereas volume overload or exercise results in eccentric growth characterized by cellular elongation and addition of sarcomeres in series. The signaling pathways that control eccentric versus concentric heart growth are not well understood. OBJECTIVE To det...

The aim of this study was ultrasound evaluation of atherosclerotic plaque morphology in relation to the degree of coronary artery lumen narrowing in patients with ischaemic heart disease. Intravascular ultrasound was performed on 38 patients (30 men and 8 women) aged 35 to 77 (average age 60 +/- 11 years old) with symptoms of ischaemic heart disease. The structure of atherosclerotic plaques wit...

Hamstring tightness is a feeling that often felt by futsal players, which can interfere with performance during playing. Previous studies suggest stretching solve it. However, hamstring associated weakness, so strengthening exercises are required to treat Strengthening consist of concentric and eccentric exercises, differ in the direction muscle contraction. This study aimed observe effect conc...

Objectives: The current study aimed at determining the immediate and long-lasting effects of eccentric concentric exercises on hypertension in individuals with high blood pressure. Methods: A total 45 hypertensive volunteers were randomly assigned to three intervention groups as exercise (n = 15), control 15) groups. All underwent interventions for four weeks, sessions per week (12 total) tread...

This research presents the modeling and analysis for the buckling and postbuckling behavior of sandwich plates under thermal and mechanical loads. The lay-up configurations of plates are laminated composite with concentric stiffener and surface mounted piezoelectric actuators. The plates are in contact with a three-parameter elastic foundation including softening and/or hardening nonlinearity. ...