In the current era of modern drug design & development via computer-aided design, potential role computational software tools is widely enlarged in use. Computer-based revolutionary new discovery process because these processes are fast, time, and cost-saving with more efficient pharmacological activity. Computer-Based mainly applied for drug-design gets many successes research. There plent...

periodic vehicle routing problem focuses on establishing a plan of visits to clients over a given time horizon so as to satisfy some service level while optimizing the routes used in each time period. this paper presents a new effective heuristic algorithm based on data mining tools for periodic vehicle routing problem (pvrp). the related results of proposed algorithm are compared with the resu...