BACKGROUND Obsessive-compulsive disorder typically begins early in life and has a chronic course. Despite the need for long-term treatment, the information about therapeutic effect on different clinical subtypes is limited. METHODS Consecutive outpatients with obsessive-compulsive disorder were evaluated for response to a two-month fluoxetine therapy course by Yale-Brown obsessive-compulsive ...

BACKGROUND Previous reports have described an association between autoimmunity and primary obsessive compulsive disorder. This study aimed to investigate any differences in the levels of T helper 1, 2, and 17 effector cell cytokines between obsessive compulsive disorder patients and the control group. METHODS The study included 34 children (23 males, 11 females), aged between 7 and 17 years, ...

Obsessive-compulsive disorder is characterized by obsessions or compulsions. Obsessions are unwanted and senseless thoughts, images, or impulses that occur repeatedly. Obsessions are experienced as unwanted and involuntary by the patient and can focus on such themes as contamination, aggression, orderliness, religion, sex:, doubt, or loss of possessions. Compulsions are ritualistic but seemingl...

Although effective treatments for obsessive-compulsive related disorders exist [1-3], nonetheless the average delay from onset of symptoms to initiating treatment is over ten years [4]. Additionally, obsessive-compulsive (OC) spectrum disorders without appropriate treatment tend to be chronic in nature [5,6]. Therefore, it is crucial that people with these spectrum disorders engage in the exist...

this study investigated the effectiveness of cognitive – behavioral therapy, drug tehrapy, and their combination in treating obsessive – compulsive disorder. twenty one patients with obsessive – compulsive disorder were randomly assigned to three groups: cognitive – behavioral , clomipramine, and combined cognitive – behavioral and clomipramine treatment groups. treatment outcomes were analyzed...

OBJECTIVE To measure the association of perfectionism with obsessive-compulsive and depressive symptoms in children and adolescents with obsessive-compulsive disorder (OCD). METHOD Sample consisted of 94 youth (44 boys, 49 girls; mean age = 13.2 y, SD = 2.5 y) with a DSM-IV diagnosis of OCD. Perfectionism beliefs were measured with both the Adaptive/Maladaptive Perfectionism Scale (AMPS) and ...

Objective: The present study describes the process of translation into Brazilian Portuguese and the cross-cultural adaptation of the Obsessive-Compulsive Inventory and the Obsessive-Compulsive Inventory-Revised scales. The Obsessive-Compulsive Inventory was developed with the purpose of measuring the intensity of the various symptoms that characterize the obsessive-compulsive disorder, assessin...

AIM To determine the extent to which mental disorders (depressive disorders, anxiety disorders, eating disorders) and psychoactive substance use are prevalent among Krakow secondary school adolescents in the late adolescent phase. METHOD A representative sample of the population of Krakow secondary school pupils was tested. Two-stage draw method identified a group of 1933 2nd form pupils of a...