Abstract Background and Aims: Vaccination of poultry has a major impact on the prevention and control of avian influenza viruses. Nanobiotechnology techniques provide a new approach for improvement of influenza vaccine efficacy. In this study, efficacy of an inactivated nano-adjuvant vaccine developed based on an endemic H9N2 virus was evaluated in SPF chickens. Materials and Methods: I...

Background: Adjuvants are used to increase the immunogenicity of new generation vaccines, especially those based on recombinant proteins. Despite immunostimulatory properties, the use of bacterial lipopolysaccharide (LPS) as an adjuvant has been hampered due to its toxicity and pyrogenicity. Brucella abortus LPS is less toxic and has no pyrogenic properties compared to LPS from other gram nega...

The impact of in vitro chemosensitivity test-guided platinum-based adjuvant chemotherapy on the surgical outcomes of patients undergoing complete resection for locally advanced non-small cell lung cancer (NSCLC) has yet to be elucidated. In the present study, the utility of adjuvant chemotherapy based on the collagen gel droplet embedded culture drug sensitivity test (CD-DST) in patients with p...

Håkan Eliasson, MD; Sven-Erik Sonesson, PhD, MD; Gurleen Sharland, MD; Fredrik Granath, PhD, MD; John M. Simpson, MD; Julene S. Carvalho, PhD, MD; Hana Jicinska, MD; Viktor Tomek, MD; Joanna Dangel, PhD, MD; Paulo Zielinsky, PhD, MD; Maria Respondek-Liberska, PhD, MD; Matthias W. Freund, MD; Mats Mellander, PhD, MD; Joaquim Bartrons, MD; Helena M. Gardiner, PhD, MD; for the Fetal Working Group ...

This topical review deals with a multidimensional gravitational model containing dilatonic scalar fields and antisymmetric forms. The manifold is chosen in the form M = M0 ×M1 × . . .×Mn, where Mi are Einstein spaces (i ≥ 1). The sigma-model approach and exact solutions in the model are reviewed and the solutions with p-branes (e.g. Majumdar-Papapetrou-type, cosmological, spherically symmetric,...