Clostridium difficile is the causative agent of the majority of antibiotic associated diarrhoea cases. C. difficile spores are recognized as the persistent and infectious morphotype as well as the vehicle of transmission of CDI. However, there is a lack of knowledge on how C. difficile spores interact with the host's epithelial surfaces. In this context, we have characterized the ability of C. ...

Introduction....................................................................................................................................2 Clostridium difficile — Biology and Pathogenesis.........................................................................2 Biology............................................................................................................................

We use data obtained with the PCA onboard RXTE to analyze the spectral variations of the black hole candidate and superluminal source GRS 1915+105. Our results suggest that despite the complicated structure of the X-ray light curve, all spectral changes observed in this source can be explained as a sudden disappearing of the inner part of the accretion disk around the compact object, followed b...

Abstract. We study inequalities connecting a product of uniform norms of polynomials with the norm of their product. Generalizing Gel’fond-Mahler inequality for the unit disk and Kneser-Borwein inequality for the segment [−1, 1], we prove an asymptotically sharp inequality for norms of products of algebraic polynomials over an arbitrary compact set in plane. Applying similar techniques, we prod...

We use data obtained with the PCA onboard RXTE to analyze the spectral variations of the black hole candidate and superluminal source GRS 1915+105. Our results suggest that despite the complicated structure of the X-ray light curve, all spectral changes observed in this source can be explained as a sudden disappearing of the inner part of the accretion disk around the compact object, followed b...

We investigate the possibility that gamma-ray bursts are powered by a central engine consisting of a black hole with an external magnetic field supported by a surrounding disk or torus. The rotational energy of the black hole can be extracted electromagnetically as a Poynting flux, a mechanism proposed by Blandford and Znajek(1977). Recently observed magnetars indicate that some compact objects...

We compute the generalized Lefschetz number of orientation-preserving selfhomeomorphisms of a compact punctured disk, using the fact that homotopy classes of these homeomorphisms can be identified with braids. This result is applied to study Nielsen-Thurston canonical homeomorphisms on a punctured disk. We determine, for a certain class of braids, the rotation number of the corresponding canoni...

We study inequalities connecting a product of uniform norms of polynomials with the norm of their product. Generalizing Gel’fond-Mahler inequality for the unit disk and Kneser-Borwein inequality for the segment [−1, 1], we prove an asymptotically sharp inequality for norms of products of algebraic polynomials over an arbitrary compact set in plane. Applying similar techniques, we produce a rela...

We present a detailed model for the formation of massive objects at the centers of galaxies. The effects of supernovae heating and the conditions of gas loss are revisited. The escape time of the gas is compared with the cooling time, which provides an additional condition not previously considered. Its consequences for the allowed mass range of the halo is calculated and parameterized in terms...

Abstract. We prove an inequality for Hölder continuous differential forms on compact manifolds in which the integral of the form over the boundary of a sufficiently small, smoothly immersed disk is bounded by a certain multiplicative convex combination of the volume of the disk and the area of its boundary. This inequality has natural applications in dynamical systems, where Hölder forms are ub...