The periosteum and Sharpey's fibre extensions occupy the musculoskeletal interface and may be strategic in age-related deterioration. Because of its exceptionally powerful insertions the porcine mandible is an ideal model and its periosteal system was compared in 4 separate regions of adult young (1 year) and older (3 year) animals. These were examined by undecalcified histology, collagen immun...

In 2007, research was carried out to determine the type and amount of asbestos fibers in a Croatian factory with a long history of making asbestos-containing products.Since the 1970s, asbestos fibres have been considered carcinogenic in humans i.e as a known cancer-causing agent. In the environment, asbestos fibres are inactive and naturally resist biodegradation. In time, fibres can only be gr...

Background & Objectives: Oral submucous fibrosis (OSMF) is a condition where excessive deposition of dense collagen fibers occurred in the connective tissue of oral mucosa. An alteration of collagen necessitates an in depth understanding of collagen in oral tissues as no breakthrough studies have been reported. Therefore the aim was to correlate the clinical, functional and histopathol...

in 2007, research was carried out to determine the type and amount of asbestos fibers in a croatian factory with a long history of making asbestos-containing products.since the 1970s, asbestos fibres have been considered carcinogenic in humans i.e as a known cancer-causing agent. in the environment, asbestos fibres are inactive and naturally resist biodegradation. in time, fibres can only be gr...

Alleged primitive feathers or protofeathers in the theropod dinosaur Sinosauropteryx have potentially profound implications concerning feather morphogenesis, evolution offlight, dinosaur physiology and perhaps even the origin of birds, yet their existence has never been adequately documented. We report on a new specimen of Sinosauropteryx which shows that the integumental structures proposed as...

Collagen fibres within the extracellular matrix lend tensile strength to tissues and form a functional scaffold for cells. Cells can move directionally along the axis of fibrous structures, in a process important in wound healing and cell migration. The precise nature of the structural cues within the collagen fibrils that can direct cell movement are not known. We have investigated the structu...

That some alteration in collagen occurs with age has been indicated by various workers. Young rat tendon (Neuberger and others, 1951) shows a greater radioactive glycine turnover than that of adult animals. Similar findings were reported in the skin of rats (Neuberger and Slack, 1953) and rabbits (Harkness and Neuberger, 1952). Under the electron microscope the collagen fibres in newborn rat sk...

Monkey periodontal ligament fibroblasts (MPLF cells), human gingival fibroblasts (HGF cells), rat embryonic calvaria cells (REC cells), porcine periodontal ligament epithelial cells (PPLE cells) and rat osteosarcoma 17/2 cells (ROS cells) were incorporated into 3-dimensional collagen gels plated in 60 mm Petri dishes in order: first, to measure the capacity of these cell types to contract; seco...

When grown in the presence of exogenous collagen I, Mycobacterium bovis BCG was shown to form clumps. Scanning electron microscopy examination of these clumps revealed the presence of collagen fibres cross-linking the bacilli. Since collagen is a major constituent of the eukaryotic extracellular matrices, we assayed BCG cytoadherence in the presence of exogenous collagen I. Collagen increased t...

BACKGROUND During labour, the cervix undergoes a series of changes to allow the passage of the fetoplacental unit. While this visible transformation is well-described, the underlying and causative microscopic changes, in which collagen plays a major role, are poorly understood and difficult to visualise. Recent studies in mice and humans have shown that Second Harmonic Generation (SHG) microsco...