CONTEXT Cognitive rehabilitation has shown efficacy in improving cognition in patients with schizophrenia but the underlying neurobiologic changes that occur during these treatments and support cognitive improvement are not well known. OBJECTIVE To examine differential changes in brain morphology in early course schizophrenia during cognitive rehabilitation vs supportive therapy. DESIGN Ran...

BACKGROUND Improving the quality of care for people with dementia and their carers has become a national priority in many countries. Cognitive Stimulation Therapy (CST) groups can be beneficial in improving cognition and quality of life for people with dementia. The aim of the current study is to develop and evaluate a home-based individual Cognitive Stimulation Therapy (iCST) programme for peo...

The central thalamus (CT) is a key component of the brain-wide network underlying arousal regulation and sensory-motor integration during wakefulness in the mammalian brain. Dysfunction of the CT, typically a result of severe brain injury (SBI), leads to long-lasting impairments in arousal regulation and subsequent deficits in cognition. Central thalamic deep brain stimulation (CT-DBS) is propo...

OBJECTIVES To systematically identify, appraise, and summarize research on the effects of behavioral interventions to prevent cognitive decline in community-dwelling older adults using a holistic wellness framework. DESIGN Systematic review of randomized controlled trials that tested the effectiveness of behavioral interventions within each of the six dimensions of wellness: occupational, soc...

The extent to which cognitive models of development and maintenance of depression apply to adolescents is largely untested, despite the widespread application of Cognitive Behavior Therapy (CBT) for depressed adolescents. Cognitive models suggest that negative cognitions, including interpretation bias, play a role in etiology and maintenance of depression. Given that cognitive development is in...

Evidence from recent studies showed that acute aerobic exercise results in improvements in different cognitive functions. The goal of this study was to assess the influence of acute bouts of aerobic versus resistance exercise on attention and executive function in adults. Thirty-nine physically active adults (age = 52±8 yr) served as participants. Each participant visited the laboratory four ti...

Globally, cases of depression and anxiety have been on the increase among adolescents. Depression interfere significantly students’ academic achievement in schools at all levels. It is more intensed mathematics learning, reason being that Mathematics as a school subject involves critical thinking, which essentially has to do with mind-(cognition). suffice say timely applications cognitive thera...

Abstract Background Aducanumab is an anti-amyloid-? (A?) antibody that achieved reduced amyloid pathology in Alzheimer’s disease (AD) trials; however, it controversial whether also improved cognition, which has been suggested would require a sufficiently high cumulative dose of the brain. Therapeutic ultrasound, contrast, only begun to be investigated human AD clinical trials. We have previousl...

OBJECTIVE Specific parental behaviors and cognitions are associated with child anxiety. Studies informing us of the directionality of the associations are lacking. We investigated the effect of parental involvement in children's anxiety treatment on parental behaviors and cognitions. METHOD Children (N=54, 7-12 years) and parents were randomly allocated to different treatment groups (involved...