this experiment was conducted to determine the effect of vitamin c (vc) and coenzyme q10 (coq10) onimmunity response of broilers in cold stress condition using 500 male chicks in a completely randomizeddesign with 5 treatments and five replicates. treatments were: positive control (pc, normal conditionsgrowth without antioxidants), negative control (nc, cold stress without antioxidants), cold s...

OBJECTIVES Coenzyme Q10 (CoQ10) deficiency syndrome is a rare condition that causes mitochondrial dysfunction and includes a variety of clinical presentations as encephalomyopathy, ataxia and renal failure. First, we sought to set up what all have in common, and then investigate why CoQ10 supplementation reverses the bioenergetics alterations in cultured cells but not all the cellular phenotype...

BACKGROUND Acute liver damage may be followed by biochemical, behavioral, and pathological alterations, which can result in serious complications and even death. OBJECTIVES In this experimental study we determined whether coenzyme Q10 (CoQ10), a common supplementary medicine known to have protective, antioxidative, and anti-inflammatory effects in cells, has any protective effect against thio...

Natural lipophilic bioactives that possess human health benefits, such as coenzyme Q10 (CoQ10) and R-α-lipoic acid (RALA), often have undesirable characteristics that limit their use as nutraceuticals and cosmeceuticals. These bioactives are usually unstable against oxygen, ultraviolet light, low pH and heat. Furthermore, their watersolubility is low because of their hydrophobic nature or insta...

Intensive physical exercise may cause muscular injury and increase oxidative stress. The purpose of this study was to examine the effect of an antioxidant, coenzyme Q10 (CoQ10), on muscular injury and oxidative stress during exercise training. Eighteen male students, all elite Japanese kendo athletes, were randomly assigned to either a CoQ10 group (n 10) or a placebo group (n 8) in a double-bli...

CoenzymeQ10 (CoQ10) is used as a food supplement and as an ethical drug because of its antioxidant functions and key role in mitochondrial bioenergetics. In this study, the effects of CoQ10 on blood biochemistry and malondialdehyde (MDA) levels in rats were investigated. Ten male Wistar rats ages ranging between 7 and 8 weeks were used. All animals were kept under the same condition and were gi...

objective(s) the present study aimed to investigate the effects of a fat soluble antioxidant, coenzyme q10 (coq10) and folic acid on learning and memory in the rats with intracerebroventricular injection of streptozotocin (icv-stz), an animal model of sporadic type of alzheimer's disease. materials and methods the lesion groups were injected bilaterally with icv-stz (1.5 mg/kg b.wt., in no...

Two pot experiments were conducted to evaluate the response of radish crops against different plant growth regulators, biostimulants, and leaf extracts at Yale University, USA. The first experiment examined marginal effect vitamin B12 when added Berlyn Laboratory’s proprietary biostimulant formula (GPB Core). Increasing concentrations added, as investigated in groups SL (0 mg/L), SB1 (0.5 SB2 (...

BACKGROUND Coenzyme Q10 (CoQ10) supplementation improves mitochondrial coupling of respiration to oxidative phosphorylation, decreases superoxide production in endothelial cells, and may improve functional cardiac capacity in patients with congestive heart failure. There are no studies evaluating the safety, tolerability and efficacy of varying doses of CoQ10 in chronic hemodialysis patients, a...

INTRODUCTION In addition to their lipid-lowering effect, statins have pleiotropic effects that may extend their use to the treatment and prevention of various other diseases such as cancer, osteoporosis, multiple sclerosis, rheumatoid arthritis, type 2 diabetes, and Alzheimer's disease. Consequently, the number of patients taking statins is expected to increase. A side effect of statins, statin...