INTRODUCTION Tenofovir has been associated with decline in kidney function, but in patients with low baseline kidney function, improvements over time have been reported. Additionally, the magnitude and trajectory of estimated glomerular filtration rate (eGFR) changes may differ according to how eGFR is calculated. We described changes in eGFR over time, and the incidence of, and risk factors fo...

We appreciate the comments by Dr O’Connell and colleagues on our article published in CHEST 1 describing the cumulative incidence and pretransplant risk factors for post-lung transplant renal dysfunction in adult patients with cystic fi brosis (CF). We agree that serum creatinine concentration alone should not be relied upon solely to assess renal function in CF because of its poor sensitivity....

BACKGROUND Cystatin C is a low molecular weight protein produced by all nucleated human cells, with a stable production rate. Its levels are not influenced by inflammation, infections, hepatic or renal diseases, or by dietary or constitutional factors. We compared serum cystatin C and serum creatinine based predicting equations to estimate glomerular filteration rate (GFR) in type 2 diabetes me...

Recent recommendations emphasize the need to assess kidney function using creatinine-based predictive equations to optimize the care of patients with chronic kidney disease. The most widely used equations are the Cockcroft-Gault (CG) and the simplified Modification of Diet in Renal Disease (MDRD) formulas. However, they still need to be validated in large samples of subjects, including large no...

Background: Urinary albumin excretion has been purported to be strongly linked cardiovascular events in hypertensive patients. The prevalence of microalbuminuria patients with essential hypertension and its relationship target organ damage was evaluated the present study, as correlation except not deliberated upon much past. Objectives: To evaluate between reduced creatinine clearance subclinic...

Background: Numerous equations are applied in order to estimate the glomerular filtration rate (GFR). Objectives: This study aimed spot optimal equation that accurately estimates GFR and, therefore, chronic kidney disease (CKD) stage renal transplant patients. Methods: cross-sectional was conducted on 58 Their venous blood samples were obtained for serum creatinine and cystatin C determination ...

Abstract Background The Cockcroft-Gault equation (CrClC-G) is recommended for dose adjustment of direct oral anticoagulant drugs (DOACs) to kidney function. We aimed assess whether defining DOACs appropriateness according various function estimators changed the associations between and adverse events in older adults with atrial fibrillation (AF). Methods Participants Berlin Initiative Study AF ...

Objective: To determine frequency and patterns of coronary artery disease in patients with glomerular hyper filtration (GHF), presented acute syndrome (ACS). Study Design: Cross Sectional, Retrospective study. Setting: Tertiary Healthcare Centre, Karachi. Period: July 2018 to 2021. Material & Methods: Twelve hundred sixty seven undergone Coronary angiography (CAG) for ACS having estimated r...