Full-field optical coherence tomography (FF-OCT) using a conventional light-emitting diode and a complementary metal-oxide semiconductor camera has been developed for characterising coatings on small pellet samples. A set of en-face images covering an area of 700 × 700 μm(2) was taken over a depth range of 166 μm. The three-dimensional structural information, such as the coating thickness and u...

In the last decades, many efforts have been made to counteract adverse effects after stenting atherosclerotic coronary arteries. A breakthrough in better vascular wall regeneration was noted in the new era of drug-eluting stents. A novel personalized approach is the development of gene-eluting stents promising an alteration in gene expression involved in regeneration. We investigated a coating ...

A difficulty with the design and operation of an electrokinetically operated DNA hybridization microfluidic chip is the opposite direction of the electroosmotic flow and electrophoretic mobility of the oligonucleotides. This makes it difficult to simultaneously deliver targets and an appropriate hybridization buffer simultaneously to the probe sites. In this work we investigate the possibility ...

Fibre-reinforced polymer matrix composites find use in most transport applications, chemical plant, renewable energy systems, pipelines and a variety of other industries. Many of these applications require a separate surface finish for cosmetic and/or durability reasons. This coating, known as the gel-coat, is normally applied onto the mould tool before the structural laminate is moulded agains...

We aimed to embed silica optical fibers in composites (epoxy vinyl ester matrix reinforced with E-glass unidirectional fibers in mass fraction of 60%) in order to further monitor the robustness of civil engineering structures (such as bridges). A simple system was implemented using two different silica optical fibers (F1-double coating of 172 µm diameter and F2-single coating of 101.8 µm diamet...

The functional success of a biomedical implant critically depends on its stable bonding with the host tissue. Aseptic implant loosening accounts for more than half of all joint replacement failures. Various materials, including metals and plastic, confer mechanical integrity to the device, but often these materials are not suitable for direct integration with the host tissue, which leads to imp...

Thermal control ceramic coatings on Mg-Li alloys have been successfully prepared in silicate electrolyte system by plasma electrolytic oxidation (PEO) method. The PEO coatings are mainly composed of crystallized Mg2SiO4 and MgO, which have typical porous structure with some bulges on the surface; OES analysis shows that the plasma temperature, which is influenced by the technique parameters, de...

This paper investigates the effects of thin plastically deformable layers embedded in an elastic coating upon debonding of a multilayer from its substrate. Such coatings are normally deposited at high temperature and cooled to ambient, resulting in significant stresses from thermal expansion mismatch. Other stresses can develop during subsequent thermal cycling if volumetric changes such as pha...

The objective of this research was to design a new colon‐targeted drug delivery system based on chitosan. The properties of the films were studied to obtain useful information about the possible applications of composite films. The composite films were used in a bilayer system to investigate their feasibility as coating materials. Tensile strength, swelling degree, solubility, biodegradation de...

An oral monolithic osmotically controlled delivery system for Nifedepine using asymmetric membrane technology was developed and evaluated. Unlike conventional osmotic systems, which require laser drilling, this system releases the drug in a controlled manner from asymmetric membrane coated core tablets. Asymmetric membrane is formed by dry process with phase inversion technology process using c...