Nasal intermittent positive-pressure ventilation (nIPPV) is used for the treatment of respiratory failure in patients with neuromuscular disease. The aim of the present study was to demonstrate that nIPPV may activate nose receptors, the consequence of which being reflex changes in lung resistance. The changes in interrupter resistances (Rint) in response to nIPPV were tested before and after l...

Experiments were performed on 2 groups of baboons anesthetized with Sernylan. One group served as control and the other was premedicated with 5 mg/kg phenoxybenzamine (PBZ). A 2-step hypovolemic shock model was used followed by retransfusion of the shed blood. Cerebral blood flow was measured by the 133Xe clearance method. Arterial and cerebral venous samples were taken and analyzed for blood g...

As long as ventilatory studies were the only approach to the problem of dyspncea in cardiac patients, its explanation seemed to be found in pulmonary changes secondary to congestive failure (Peabody and Wentworth, 1917). Combined ventilatory and circulatory measurements in such patients showed the problem to be more complex. Reduced ventilatory capacity appears to become a significant factor in...

Objective: This study aimed to investigate the impact of tocilizumab, an IL6R inhibitor, on clinical features and laboratory tests subjects admitted with severe COVID-19 respiratory failure.
 Material Methods: A total 30 patients positive polymerase chain reaction for failure were analyzed in a retrospective manner. All received 8mg/kg body weight tocilizumab i.v. once addition standard tr...

Due to high surface area, low density, open pore structure and excellent insulation properties aerogels were intensively investigated in the past decades for diverse range of applications. The state of the art of aerogel production by supercritical drying is to produce monolithic aerogel, where the sol is aged in molds and dried by extraction with supercritical CO2. Aerogels in form of spherica...

Striking alterations in respiratory gas and blood ammonia levels usually accompany hepatic coma. The arterial pH is elevated and the carbon dioxide tension reduced (1). The blood ammonia level (2-4) is increased in many instances and the brain arteriovenous ammonia difference is high (5, 6). The cerebral oxygen uptake is depressed (7, 8). Whether the pronounced alkalosis which accompanies many ...

BACKGROUND Therapeutic gases and other modalities delivered by inhalation may affect the accuracy of capnographic measurements in 2 ways. First is the specificity of the measurement of CO2 within the device, and second is the dilution effect of supplemental gases in the ambient air during CO2 sampling by the device. Our goal was to determine if variables such as inhaled gas composition, gas flo...

OBJECTIVES The underlying mechanisms of panic attacks (PA's) are still unclear. Theories focusing on these mechanisms differ in their description of the relationship between panic and fear. The main controversy concerns whether a PA resembles the classical flight response, or whether it is qualitatively different from fear. According to the first theory, a PA would result in hypothalamic-pituit...