نتایج جستجو برای: cns tumors
تعداد نتایج: 279888 فیلتر نتایج به سال:
Abstract BACKGROUND Effective immunotherapy against tumors of the central nervous system (CNS) requires that drug blood brain barrier (BBB) and encounter immune cells. We have previously described a mechanism which may facilitate transport CD3-engaging therapeutics into CNS, via carriage on activated T Building this, we sought to produce specific cell phenotypes rapidly enter accumulate in CNS....
Central nervous system (CNS) germ cell tumors (GCT) have not been epidemiologically well described. Our study describes 2 population-based series of nonpineal CNS GCT. Data on all primary (malignant and nonmalignant) CNS (ICD-O-3 sites: C70.0-C72.9, C75.1-C75.3) GCT diagnosed between 2000 and 2004 from the Central Brain Tumor Registry of the United States (CBTRUS) and on all malignant GCT diagn...
von Hippel-Lindau disease (VHL) is a familial neoplasia syndrome associated with multisystem tumor development. Depending on tumor type and location, current treatments for VHL-associated tumors can include a combination of chemotherapy, radiation therapy, and/or surgery. Central nervous system (CNS) manifestations of VHL include craniospinal hemangioblastomas and endolymphatic sac tumors (ELST...
Central nervous system (CNS) tumors are the most common solid tumors in childhood. Since the sensitivity of combined cerebrospinal fluid (CSF) cytology and radiological neuroimaging in detecting meningeal metastases remains relatively low, we sought to characterize the CSF proteome of patients with CSF tumors to identify biomarkers predictive of metastatic spread. CSF samples from 27 children w...
Abstract BACKGROUND High-grade gliomas (HGG) in young children pose a challenge due to favorable but unpredictable outcomes. While retrospective studies have broadened our understanding of tumor biology, prospective data regarding outcomes and molecular predictors is lacking. METHODS Young (0-5 years) histologically diagnosed with HGG enrolled on the SJYC07 trial or treated at St Jude Children’...
The clinical outcomes for infants with malignant tumors are often worse than older children due to a combination of more biologically aggressive disease in some cases, and increased toxicity-or deintensification therapies concern toxicity-in others. Especially very young children, finding the appropriate balance between maximizing treatment efficacy while minimizing particular late side effects...
PURPOSE To determine the maximum tolerated dose of single fraction radiosurgery in patients with recurrent previously irradiated primary brain tumors and brain metastases. METHODS AND MATERIALS Adults with cerebral or cerebellar solitary non-brainstem tumors </= 40 mm in maximum diameter were eligible. Initial radiosurgical doses were 18 Gy for tumors </= 20 mm, 15 Gy for those 21-30 mm, and ...
Abstract Background There is great interest in utilizing nanoparticles to improve drug delivery central nervous system (CNS) tumors, but the biologic features underlying successful at tumor site are not known. METHODS We developed a pooled screening assay investigate cellular predictive of nanoparticle and screened 35 fluorescent formulations against 488 cancer cell lines with DNA barcodes. The...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید