BACKGROUND Human pregnancy offers an immunological challenge for the immunocompetent women accommodating an allogenic fetus, while continuing to combat potentially infectious disease. Cytomegalovirus (CMV) infects the majority of the human population and establishes lifelong persistence, which can lead to the oligoclonal expansion of differentiated T cells. Primary CMV infection and, less commo...

The prevalence of cytomegalovirus (CMV) in HIV infected patients is 90%. Both CMV and HIV are involved in the pathogenesis of metabolic and cardiovascular diseases. The study retrospectively evaluated the correlation of CMV infection with lipodystrophy (LD) and hypertension (HTA) in HIV patients who have been beneficiaries of medical care in Galați, during 2013. The evolution of anthropometric ...

1 This study aimed to evaluate the use of Protein A-peroxidase (HRPO) in indirect ELISA 2 (iELISA) and IgG avidity assays for serological distinction between Brucella abortus S193 vaccinated and infected cows. Four groups were analyzed: (GI) 41 non-vaccinated seropositive 4 cows; (GII) 79 S19-vaccinated heifers analyzed at 3 months post-vaccination; (GIII) 105 S195 vaccinated cows analyzed afte...

This case-control study investigated whether previous infection with cytomegalovirus (CMV) was associated with coronary heart disease (CHD). In total, 312 patients of German nationality aged 40-68 years who had a coronary stenosis of >50% of the luminal diameter were recruited for study. Controls (n=479) were voluntary blood donors. CMV serology was performed to determine presence of specific C...

Background and Aims: Cytomegalovirus (CMV) has worldwide distribution, and its prevalence rate depends on factors such as economic and geographical conditions. An important way of the virus transmission is via blood. Due to high prevalence of anti-CMV antibodies in blood donors and lack of data concerning its seroprevalence in the region, this study was carried out to determine the prevalence r...

nfection brought about by Toxoplasma gondii (T. gondii), toxoplasmosis, is transmitted to the fetus via the placenta. Infection may progress in the expectant mother totally asymptomatically. However, such infections are particularly significant because of undesired consequences for the fetus. Immunoglobulin G (IgG) avidity tests, which have come into use in recent years, make it possible to dis...

Maternal antibodies may protect the fetus and neonate against severe forms of CMV-caused disease, therefore this study investigated the efficiency of the placental transfer of naturally acquired, maternal total anti-cytomegalovirus (CMV) IgG and neutralizing antibodies at different gestational ages. The study was conducted on 182 healthy CMV-seropositive Brazilian mothers and their 196 infants ...