نتایج جستجو برای: clonal population
تعداد نتایج: 714788 فیلتر نتایج به سال:
T cell clonal anergy induction in lymphopenic nu/nu mice was found to be ineffective. Exposure to a tolerizing peptide Ag regimen instead induced aggressive CD4(+) cell cycle progression and increased Ag responsiveness (priming). Reconstitution of T cell-deficient mice by an adoptive transfer of mature peripheral lymphocytes was accompanied by the development of a CD25(+)Foxp3(+)CTLA-4(+)CD4(+)...
Although tumor-initiating cell (TIC) self-renewal has been postulated to be essential in progression and metastasis formation of human pancreatic adenocarcinoma (PDAC), clonal dynamics of TICs within PDAC tumors are yet unknown. Here, we show that long-term progression of PDAC in serial xenotransplantation is driven by a succession of transiently active TICs producing tumor cells in temporally ...
African trypanosomes are unusual among pathogenic protozoa in that they can undergo their complete morphological life cycle in the tsetse fly vector with mating as a non-obligatory part of this development. Trypanosoma brucei rhodesiense, which infects humans and livestock in East and Southern Africa, has classically been described as a host-range variant of the non-human infective Trypanosoma ...
Population-based studies on Staphylococcus aureus nasal colonization are scarce. We examined the prevalence, resistance, and molecular diversity of S. aureus in the general population in Northeast Germany. Nasal swabs were obtained from 3,891 adults in the large-scale population-based Study of Health in Pomerania (SHIP-TREND). Isolates were characterized using spa genotyping, as well as antibio...
Candida auris is an emerging multidrug resistant yeast that causes nosocomial fungaemia and deep-seated infections. Notably, the emergence of this yeast is alarming as it exhibits resistance to azoles, amphotericin B and caspofungin, which may lead to clinical failure in patients. The multigene phylogeny and amplified fragment length polymorphism typing methods report the C. auris population as...
Heterogeneity is widespread in natural environments; as a result, connected clonal ramets often live areas characterized by patches of different resources. Specifically, plants are frequently affected conditions heterogeneous water stress. This raises the question how grow and reproduce with In this study, we investigated adaptation mechanisms under environmental conditions. On one hand, bore m...
We evaluated three possible functions of clonal growth related to genet persistence in the root-suckering understory tree pawpaw, Asimina triloba (L.) Dunal: (1) risk spreading through multiplication of stems, (2) enhanced establishment and survival of new stems, and (3) horizontal expansion growth of patches. The number, diameter growth, and spatial distribution of annual stem recruits were ex...
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